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Ramping Up to Multiscale: Taking Biomedical Modeling to a New Level

Multi-scale modeling is now at what might be called its gestational stage

For centuries, mathematics has been an indispensable ally of the physical sciences and engineering. Planes fly and telephones work because engineers know how to simplify physical systems into...
Apr, 01, 2006
Visualization in Space and Time: Seamless Pipelines Now Available

Advances in visualization changing work flows for understanding molecular dynamics, tracking cell movements, and designing interventional procedures

The pathway from raw data to valuable visualization of molecules, cells or organs being simulated over time involves several potentially painstaking steps. Typically, researchers must generate a set...
atrial fibrillation, developmental biology, ePMV, patient-specific, visualization
Sep, 02, 2011
Dogs, Doses, and Devices: The FDA's Ambitious Plans for Computational Modeling

Computational modeling can help fill gaps in how we develop and review new drugs and devices

What role does computational modeling play at the United States Food and Drug Administration (FDA)?  If you ask Paul Watkins, MD, director of the Hamner—University of North Carolina...
devices, drug discovery, FDA, modeling
Sep, 01, 2011
Smart Embedded Devices: Here They Come

Machine learning for an artificial pancreas and deep brain stimulation

Embedded medical devices that both detect symptoms and treat them have existed for decades. Take, for example, the heart pacemaker. But a new generation of implants could soon emerge to do something...
diabetes, epilepsy, machine learning, pancreas, Parkinsons
Oct, 19, 2012
The Physiome: A Mission Imperative

To understand biology—and provide appropriate medical care—scientists need to understand interactions across multiple scales. Hence the Physiome.

This is the reality of human biology: events span a 109 range in lengthscale (molecular to organismal) and a 1014 range in timescale (molecular movement to years). To understand this biology—...
Jun, 01, 2010

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