Synthetic biology moves beyond the whiteboard.
In synthetic biology labs around the world, brainstorming has often begun at the same place: in front of a whiteboard. Marker in hand, researchers jot down the parts needed to form a new circuit,...
Jun, 18, 2014
Confidence boost for modelers
It’s often said that all models are wrong, but some are useful. And one model that certainly falls in the “useful” category is the human lower-limb model that Scott Delp published...
Jun, 01, 2010
Pursuing the frontiers of systems biology in an interdisciplinary, non-academic enviroment
The Institute for Systems Biology (ISB) was founded in Seattle, Washington in 2000 by Leroy Hood, MD, PhD, Alan Aderem, PhD, and Reudi Aebersold, PhD. Five years later, they are pursuing the...
Apr, 01, 2006
Scientists have long wondered how many genes are necessary to support life. This knowledge could be used to construct new forms of artificial life to efficiently produce better biofuels or drugs....
Jan, 01, 2008
Biomechanical models contribute to a better understanding of both the normal and the diseased eye.
Squint, and you can almost make out that bird soaring over the horizon. But determining whether it’s a hawk or a raven will be nearly impossible for someone with myopia, also known as...
Feb, 19, 2013
A Model for Extracting Literature-based Knowledge
Too much scientific knowledge is buried in published literature. Case in point: The phylogenetic relationships among microbial species are locked into numerous publications about individual species...
Nov, 11, 2017
The importance of developing and deploying tools for the quantitative clinician scientist
The word Om (or Aum) has many meanings in ancient Hindu philosophy, one of which is “that which contains all other sounds.” The meaning has relevance to the now commonly used suffix...
Jun, 01, 2010
CompuCell-3D models behaviors rather than genes
Researchers have successfully simulated how growing blood vessels affect the sizes and shapes of tumors using a 3-D model based solely on how cells behave—without reference to intracellular...
Jan, 01, 2010
Algorithm joins related publications in a chain from start to finish
A good story ties up all the loose ends. A new data-mining tool takes a stab at doing the same. Dubbed storytelling, the algorithm may make it easier to unearth unexpected connections in the...
Jan, 01, 2007
Moving from intuition to evidence-based intervention
To understand how muscles contract and joints flex, researchers have dissected cadavers and experimented with animals. They can describe how bones, muscles, and tendons connect in a complicated...
Jan, 01, 2007
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