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LIFE IS CROWDED: Modeling the Cell's Interior

Modelers are using recent gains in computational power to consider the complex interactions of hundreds or thousands of macromolecules at once--a necessary first step toward whole cell simulation

Molecules in cells behave like people in crowded subway cars. Because they can barely budge or stretch out without bumping into a neighbor, they move more slowly, smush themselves into more compact...
crowding, macromolecule, molecular dynamics
Apr, 01, 2011
Simulating Crowded Cytoplasm

Model fits experimental evidence

In biology textbooks, the carefully rendered cross-section of an E. coli cell often resembles a well-organized and spacious apartment, with everything in its place and ample room for movement. But a...
Jun, 01, 2010

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