Can the complexities of biology be boiled down to Amazon.com-style recommendations? The examples here suggest possible pathways to an intelligent healthcare system with big data at its core.
“We have recommendations for you,” announces the website Amazon.com each time a customer signs in.
This mega-retailer analyzes billions of customers’ purchases—nearly $...
Jan, 02, 2012
Researchers are not simply retrieving and repackaging what is already known, but are also deriving new knowledge by discovering connections that were previously unnoticed.
Not long ago, reading biomedical literature involved hours in the library combing through rows of dusty periodicals—not to mention pocketfuls of change for the copy machine. Now, although the...
Jul, 01, 2008
Six startups jockey for a place at the table. Who will succeed?
A handful of startups are wagering that genome interpretation is the next big thing.
Why is this business space so hot? “Once you can produce a better faster genome, thanks...
Jun, 20, 2013
Database automatically mines literature for drug-gene relationships--and does it as well as manually curated databases.
When a drug saves one person but makes another ill, a bitter lesson in genetic differences often follows. With many such lessons already under our collective belts, researchers are using existing...
Jan, 01, 2010
Researchers are expanding the types of data that can be used to predict infectious disease spread; developing novel ways to analyze that data; and trying to create systems that can help address public health problems today
American officials are seeking better ways to anticipate public health crises following ten years that have seen outbreaks of SARS, avian flu, H1N1, West Nile virus, cholera and, most recently,...
Apr, 01, 2011
Today, the knowledge, experience and memory of clinicians or scientists function as the exclusive resource for distinguishing normal from abnormal brain images; identifying signatures or biomarkers...
Jul, 01, 2009
An exploration of data-driven and process-driven approaches to data privacy
Trust. It’s the basis of every patient/physician interaction: Shared personal health information is kept confidential and used only for the patient’s benefit. It’s a tradition that...
Jan, 02, 2012
Looking inside the cell without opening it
When light hits an obstacle, its scattering pattern reveals information regarding the internal structure of the obstacle. If that obstacle is a cell, the scattering pattern might indicate whether the...
Jun, 01, 2005
New approaches extend multiscale models to represent cellular mesoscales and bridge from molecular to cellular models
In an era of increasingly comprehensive molecular characterizations of living systems, computation has emerged as a key technology to facilitate integrative understanding of biological mechanisms....
Feb, 19, 2013
It’s impossible to predict what the hottest new tools will be, but here are a few gems that caught our attention
Many experimental researchers rely on computational tools to push the pace and productivity of laboratory research. It’s impossible to predict what the hottest new tools will be, but this...
Apr, 01, 2011
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