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Computing Gene Interactions: Functional and Statistical Approaches Converge

Epistasis explored

When people work together, some individuals may hinder team performance—essentially masking the abilities of other members—while others may boost the group’s performance beyond the...
epistasis
Sep, 01, 2011
Modeling Sex’s (Evolutionary) Appeal

Computer model supports one theory of why sex is such a good idea

Sex is a costly undertaking. Finding partners takes time and energy. Sexual contact can transmit disease. And if reproductive success is measured by how many genes you pass on, females would be...
Jul, 01, 2007
From SNPs to Prescriptions: Can Genes Predict Drug Response?

Decades of steady progress in pharmacogenetics have unearthed hundreds of associations between genes and drug response. But the field has to solve some theoretical and practical issues before it can deliver on the promise of personalized drug therapy.

As algorithms go, it’s deceptively simple. Just add together eight weighted pieces of patient information—age, height, weight, race, data about two genes, and a pair of clinical...
Jul, 01, 2009

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