Simulations illuminate the inner workings of blood at multiple levels
Understanding blood flow and coagulation is crucial to treating blood disorders such as hemophilia and thrombosis, and to dealing with diseases such as AIDS, malaria, and diabetes that have...
Jun, 07, 2012
Computation helps evaluate the nature of the NIH research portfolio in ways that were previously very difficult.
What biomedical research does the federal government fund? How is it allocated across important diseases? Has that changed over time? Answering these questions at any level of detail is tougher than...
Jun, 08, 2012
How to deal with too many dimensions and too few samples.
Noninvasive experimental techniques, such as magnetic resonance (MR), infrared, Raman and fluorescence spectroscopy, and more recently, mass spectroscopy (proteomics) and microarrays (genomics) have...
Sep, 01, 2005
Disentangling the different types of skeptics and what modelers can learn from each.
What are the telltale signs of a modeling talk at a biology conference? Just look for the sighs, shifting, and eye-rolling in the audience, says Donald C. Bolser, PhD, professor of physiological...
Jun, 05, 2012
The National Institutes of Health are on a mission: To understand and tackle the problems of human health. To make that daunting problem approachable, 15 of the 20 institutes divvy up human health...
Oct, 05, 2012
Computation offers a window into a disease often described as a black box
The growing threats of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) are spurring worldwide interest in faster and more innovative research approaches, such as...
Jun, 06, 2012
Epistasis explored
When people work together, some individuals may hinder team performance—essentially masking the abilities of other members—while others may boost the group’s performance beyond the...
Sep, 01, 2011
They're more than just pretty pictures adorning office walls and presentation slides. Beamed into operating room computer monitors, they're guiding the scalpels of brain surgeons. Dancing...
Jan, 01, 2012
As algorithms evolve, computing power explodes, and scientists solve a greater number of 3-D protein structures, computer-aided design has the potential to dramatically cut the cost and time of drug discovery
Once upon a time, not long ago, HIV/AIDS was a scourge, killing anyone who contracted the deadly virus. Now, many people are living with the disease, which they control with drugs initially developed...
Jul, 01, 2007
As barriers to massive imaging collections fall, researchers can look at human systems in their entirety rather than in pieces
In the beginning there was the Visible Human. It broke new ground by gathering some 2,000 serial images from a death row inmate’s cadaver, and was the first time researchers had sectioned a...
Jul, 01, 2007
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