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Modeling Sperm: The Finer Points of Fertilization

Navigating the oviduct and other mysteries

The essential elements of human fertilization are clear: sperm swim through the uterus, travel up the fallopian tube, and fertilize an egg. Not as well understood are the the nitty-gritty details of...
agent-based models, fertilization, sperm
Jun, 19, 2013
A Review of the Review

What this magazine has covered so far.

This, the sixth issue of this magazine (and the final issue of Volume 2), provides a good opportunity for reflection on where we’ve been and where we’re headed.  Three years ago, the...
Jul, 01, 2006
Santa Fe Institute: Addressing Complexity

A safe haven for asking fundamental, wide-ranging questions

In the summer, it can be hard to find a place to sit at the Santa Fe Institute. Much of the year, only about a dozen researchers make their home at the multidisciplinary research organization. But in...
Oct, 01, 2006
OpenMM User Profile: Jesus Izaguirre, PhD

Notre Dame’s Jesus Izaguirre collaborates with Simbios to increase the time scales of protein folding simulations with OpenMM. Why team up with Simbios? Because “they are working on exciting problems and have good people,” he says.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Jesus Izaguirre, PhD, associate professor of computer science and engineering at the...
Oct, 01, 2009
On Your Mark, Get Set, Build Infrastructure: The NCBC Launch

The first four National Centers for Biomedical Computing take off

WHY NATIONAL CENTERS? Four National Centers for Biomedical Computing were launched by the NIH in 2004 with $20 million in funding for each center over five years. The reason: We need to make...
Jun, 01, 2005
The Active Transport of Ideas

Researchers examine the connection between editorial boards of medical informatics and bioinformatics journals

How ideas spread gets at the very fabric of scholarly research and has been studied from many different angles.   Many studies examine person-to-person connectivity in social networks. Within a...
Jul, 01, 2007
Simulating Cells in Context: Bringing Mechanics Into Play
Like humans, cells are affected by their physical environment, their neighbors, the context in which they exist. Much research has focused on the chemical signals that control cell behavior. But...
developmental biology
Sep, 01, 2011
More Than Fate: Computation Addresses Hot Topics in Stem Cell Research

Using computational models, researchers are gaining traction toward understanding what makes a stem cell a stem cell; how gene expression drives stem cell differentiation; why studying stem cell heterogeneity is important; and, ultimately, how stem cells control their fate.

To the casual observer, stem cells offer the almost magical promise of—Voila!—turning into exactly the kind of cell needed to repair an injured spinal cord or replace a damaged organ. And...
stem cell
Apr, 01, 2010

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More Than Fate: Computation Addresses Hot Topics in Stem Cell Research

Using computational models, researchers are gaining traction toward understanding what makes a stem cell a stem cell; how gene expression drives stem cell differentiation; why studying stem cell heterogeneity is important; and, ultimately, how stem cells control their fate.

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