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Imaging Collections: How They're Stacking Up

As barriers to massive imaging collections fall, researchers can look at human systems in their entirety rather than in pieces

In the beginning there was the Visible Human. It broke new ground by gathering some 2,000 serial images from a death row inmate’s cadaver, and was the first time researchers had sectioned a...
Jul, 01, 2007
Bringing the Fruits of Computation to Bear on Human Health: It’s a Tough Job but the NIH Has to Do It
The National Institutes of Health are on a mission: To understand and tackle the problems of human health. To make that daunting problem approachable, 15 of the 20 institutes divvy up human health...
Oct, 05, 2012
Diffusion Tensor Imaging Tractography: Revealing Connectivity in the Living Brain
One of the major obstacles to studying the human brain has always been gaining access. Until relatively recently, almost all of what we knew about the brain was obtained through post-mortem ...
Apr, 01, 2008
Implicit Representation of Biological Shapes and Forms
  Imaging, geometric modeling, representation and computing of shapes and forms are important components of modern computational biology. These processes apply across wide spectra of scales,...
Oct, 03, 2012
Infrastructure and Workforce Needs in Biomedical Informatics and Computational Biology
In science, there is a need to balance research in domain sciences and the infrastructure to support that research. Basic research mediated through peer review is understood to produce useful...
Jan, 01, 2007
From Sight to Insight: Visualization tools yield biomedical success stories
They're more than just pretty pictures adorning office walls and presentation slides. Beamed into operating room computer monitors, they're guiding the scalpels of brain surgeons. Dancing...
Jan, 01, 2012
On Your Mark, Get Set, Build Infrastructure: The NCBC Launch

The first four National Centers for Biomedical Computing take off

WHY NATIONAL CENTERS? Four National Centers for Biomedical Computing were launched by the NIH in 2004 with $20 million in funding for each center over five years. The reason: We need to make...
Jun, 01, 2005
Computing the Ravages of Time: Using Algorithms To Tackle Alzheimer’s Disease

Biomarker research, genetics, and imaging are all coming into play

In 1906, at a small medical meeting in Tübingen, Germany, physician Alois Alzheimer gave a now-famous presentation about a puzzling patient. At age 51, Auguste D.’s memory was failing...
Oct, 01, 2007
Digging Into Pixels: Radiogenomics Extracts Meaning

Seeking a non-invasive approach to cancer diagnosis and prognosis

In a radiological image, a tumor’s edges might appear fuzzy or crisp; its shape could range from oval to many-lobed; and its density and texture might vary across the tumor. To determine...
imaging, radiogenomics
Jun, 19, 2013
Mutual Information
Mutual information (MI) is defined in information theory as a measure of the dependencies between two random variables. There are many biomedical applications in which it is beneficial to quantify...
Jul, 01, 2007
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