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LIFE IS CROWDED: Modeling the Cell's Interior

Modelers are using recent gains in computational power to consider the complex interactions of hundreds or thousands of macromolecules at once--a necessary first step toward whole cell simulation

Molecules in cells behave like people in crowded subway cars. Because they can barely budge or stretch out without bumping into a neighbor, they move more slowly, smush themselves into more compact...
crowding, macromolecule, molecular dynamics
Apr, 01, 2011
An Unfolding Story

A model of chromatin explores how it folds and unfolds

To fit an organism’s DNA into a single cell, it has to be tightly compacted, first wound around proteins to form chromatin fibers, then further coiled into chromosomes. Computer simulations by...
Sep, 01, 2005

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