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Learning about cells by examining how they scatter light

Looking inside the cell without opening it

When light hits an obstacle, its scattering pattern reveals information regarding the internal structure of the obstacle. If that obstacle is a cell, the scattering pattern might indicate whether the...
Jun, 01, 2005
2012 Update on the National Centers for Biomedical Computing

The Principal Investigators weigh in

Ever since the National Institutes of Health (NIH) began funding the National Centers for Biomedical Computing (NCBCs) just over seven years ago, these powerhouses have been plugging away, building...
NCBC
Feb, 29, 2012
Three New Centers
The National Institutes of Health Roadmap for Medical Research has recently completed the first stage of an ambitious program to expand the computational infrastructure and software tools needed to...
Jan, 01, 2006
NCBCs Take Stock and Look Forward: Fruitful Centers Face Sunset

From hardened software to scientific productivity, the NCBCs have changed the landscape for biomedical computing.  What will happen when their funding expires?

It has been eight years since the National Institutes of Health (NIH) funded the first National Centers for Biomedical Computing (NCBCs). With two or three years remaining in the program (...
ccb, i2b2, Magnet, na-mic, ncbo, NCIBI, Simbios
Oct, 19, 2012
Twin Curses Plague Biomedical Data Analysis

How to deal with too many dimensions and too few samples.

Noninvasive experimental techniques, such as magnetic resonance (MR), infrared, Raman and fluorescence spectroscopy, and more recently, mass spectroscopy (proteomics) and microarrays (genomics) have...
Sep, 01, 2005
3D Radiology—Who Knew It Could Look So Good

3D images help physicians design appropriate interventions.

Images of realistic and colorful 3D human body parts line the hall outside the lab. Blood and muscle look like blood and muscle; bone looks like bone. You almost expect to find human cadavers being...
cardiovascular, radiology, stent, visualization
Sep, 01, 2011
Tapping the Brain: Decoding fMRI

How researchers are predicting specific thoughts from brain activity

Revealing the brain’s hidden stash of pictures, thoughts, and plans has, until recently, been the work of parlor magicians. Yet within the last decade, neuroscientists have gained powerful...
fMRI, memories, multivoxel pattern analysis, MVPA, neuroscience
Jan, 02, 2012
Cooking Cancer With Gold Nanoshells

Computationally modeling the hot spots

Tiny gold particles that absorb laser light and convert it into heat are a promising therapy for destroying tumors. However, controlling the temperature of such gold nanoshells is crucial: The shells...
Jan, 01, 2010
Diffusion Tensor Imaging Tractography: Revealing Connectivity in the Living Brain
One of the major obstacles to studying the human brain has always been gaining access. Until relatively recently, almost all of what we knew about the brain was obtained through post-mortem ...
Apr, 01, 2008
Predicting Brain Response To Nouns

Capturing meaning in functional MRI

Thinking of a noun—a peach, train, or bird, for example—activates specific parts of the brain.  Now, scientists have trained a computer to predict such activation patterns. The...
Oct, 01, 2008
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