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Molecular Biology Wikis Launched

Central repository of information on genes and proteins requires participation by the scientific community

If you build it, will they come? That’s the question on everyone’s mind after the launch of two pioneering initiatives in community annotation: WikiProteins and Gene Wiki, announced,...
Oct, 01, 2008
FOLLOW THE MONEY: Big Grants in Biomedical Computing

Several big-dollar initiatives received NIH funding in late 2010

In the current economic climate, every research dollar counts. Fortunately, when it comes to biomedical computing, not everyone has been left counting change. Several big-dollar initiatives received...
brain, immunity, network
Apr, 01, 2011
NewsBytes: Winter 2005-2006
T-Rex in the Slow Lane by Kristen Cobb   Tyrannosaurus rex is often pictured baring its teeth, crouching, and running swiftly after its prey, but these images are largely based on human fancy...
Jan, 01, 2006
On Simulating Growth and Form

Simulations can teach us how young bodies and faces develop; how an artery compensates for decades of fatty plaque deposits by growing and thickening its walls; how tissue engineers can best coax endothelial cells to develop into organized sheets of skin for burn patients; and how cancerous tumors invade neighboring tissue.

For better or for worse, and on many levels, our tissues never stop growing and changing. While developing from childhood to old age, we grow not only bone, cartilage, fat, muscle and skin, but also...
Apr, 01, 2008
A Tipping Point for Function Prediction
There comes a tipping point in systems-biology studies of gene function where knowing some genes’ functions can, using a computational approach, help hone in on the functions of other genes....
Apr, 01, 2010
Biological Evidence for Turing Patterns

Mouse hair development patterns follow Turing's predictions

In the 1950s, computer science pioneer Alan Turing suggested an elegantly simple mechanism for how biological patterns such as scales, feathers, and hair might form. Now, more than fifty years later...
Apr, 01, 2007
Simulating Crowded Cytoplasm

Model fits experimental evidence

In biology textbooks, the carefully rendered cross-section of an E. coli cell often resembles a well-organized and spacious apartment, with everything in its place and ample room for movement. But a...
Jun, 01, 2010
Point/Counterpoint: Should there be a separate funding mechanism for the development and maintenance of software and infrastructure?
  POINT/   NO:  Grant applications for the development and maintenance of software and infrastructure should compete with basic research applications. Biomedicine has a strong...
Jul, 01, 2009
Computing Has Changed Biology Forever

And people are starting to notice

In 1991, a prescient editorial in Nature by Harvard’s Walter Gilbert, PhD, (“Towards a paradigm shift in biology”) included these observations on the utility and impact of computing...
Apr, 01, 2006
Watching Blood Vessels Grow and Shrink

2-D simulation shows angiogenesis as it happens

Microscopic capillaries grow on demand, snaking toward hungry cells needing their blood supply. Understanding how to control this process could help scientists promote wound healing or halt cancer in...
Jan, 01, 2007
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