Pattern-classifiers interpret fMRI data
Peek inside the skull of a couch potato watching reruns on TV and you’ll see non-stop patterns of blood flow throughout the brain. If you learn to pick out which activity patterns match up with...
Oct, 01, 2010
Making reproducible research accessible to people who don’t write code
A particular mashup of data and tools produces the unique results found in each computational biology publication. Now, researchers have developed a model system that gives readers—especially...
Apr, 01, 2010
How researchers are predicting specific thoughts from brain activity
Revealing the brain’s hidden stash of pictures, thoughts, and plans has, until recently, been the work of parlor magicians. Yet within the last decade, neuroscientists have gained powerful...
Jan, 02, 2012
How researchers are combining disparate data types and simulating systems that contain many different moving parts
13 years ago Markus Covert, PhD, read a New York Times article that changed his life. The article quoted a prominent microbiologist who suggested that the ultimate test of one’s...
Feb, 16, 2013
The complexity and variability of aging itself, along with the fragmented nature of researchers’ current understanding of aging, call for tools that can help scientists dig through mounds of data to find often subtle connections.
Jeanne Louise Calment of Arles, France rode a bicycle until she was 100 years old. When she gave up smoking at age 117, her doctor suspected it was out of pride. (She couldn’t see well enough...
Apr, 01, 2008
A grant to develop software tools to analyze how neurons distribute themselves within the brain
Do neurons need personal space like people in an elevator? Are they influenced by their neighbors or do they randomly find a home in the brain? If the arrangement is patterned, what is the cause of...
Jun, 01, 2005
Open Source reflections; designing with code re-use; and Cygwin
Do you have a few favorite books that you recommend to anyone with an interest in biomedical computing? Are there software products or Web sites that you love to evangelize? We’d like to open...
Sep, 01, 2005
Incremental progress and measured successes
Personalized cancer therapy is now a reality. A handful of tumor-classifying tests and targeted drugs are in widespread clinical use; and early attempts are underway to match high-risk cancer...
Jan, 02, 2012
"Fold-It" players find best protein conformations to fight cancer
When it comes to folding proteins, even modern supercomputers don’t always get things exactly right. Enter FoldIt, an online video game that harnesses the human brain’s natural pattern-...
Jan, 01, 2010
Connectivity Map helps connect drugs and diseases
Normal cells, diseased cells and cells on drugs share a common language: They all produce their own patterns of gene expression. And the patterns can be compared in useful ways—given a disease...
Jan, 01, 2007
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