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Cancer Proteins Show Off Their Networking Skills

Cancer proteins highly interactive

New research suggests that cancer proteins, like influential people, have the most connections. These results, from an extensive study of how human proteins interact with one another, could help...
Jan, 01, 2007
The Top Ten Advances of the Last Decade & The Top Ten Challenges of the Next Decade

A recognition of biocomputing's successes and a prediction of what's to come

The last ten years have seen huge leaps in biomedical computing. We now have new ways to integrate and understand vast quantities of data; the capacity for multi-scale biological modeling; and a...
bioinformatics tools, biomedical computing, CAD, computational modeling, data mining, disease surveillance, dynamic modeling, education, eric jakobsson, function prediction, genetic association, genome annotation, in silico screening, medical informatics, neuromodeling, prosthetics, sequence alignment, structure prediction, systems biology, systems biomedicine, telemedicine, tomography
Jun, 01, 2005
Where Tuberculosis Meets Computation: 10 Points of Intersection

Computation offers a window into a disease often described as a black box

The growing threats of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) are spurring worldwide interest in faster and more innovative research approaches, such as...
Jun, 06, 2012
Scale-Free Networks in Contemporary Biology
A standard dictionary definition of a network is “an interconnected or interrelated chain, group, or system.” A cursory look at our surroundings shows that networks are ubiquitous. For...
Oct, 01, 2007
Leveraging Social Media For Biomedical Research

How social media sites are rapidly doing unique research on large cohorts

It has become commonplace for people to use social media to share their healthcare stories, seek a community of individuals with the same diseases, and learn about treatment options. All this...
ALS, clinical trials, GWAS, Parkinsons, social media
Jan, 02, 2012
Sensational Sequences

A new media artwork explores novel ways to represent and intuitively understand nature in the metagenomic era

What’s it like to be immersed in a dataset of millions of DNA sequences? Audiences of ATLAS in silico—a new media artwork that explores novel ways to represent and intuitively understand...
Oct, 01, 2008
Infrastructure and Workforce Needs in Biomedical Informatics and Computational Biology
In science, there is a need to balance research in domain sciences and the infrastructure to support that research. Basic research mediated through peer review is understood to produce useful...
Jan, 01, 2007
Bayesian Networks: A Quick Intro
Advances in technology have brought to molecular biology datasets that are bigger, more sophisticated, and, unfortunately, more difficult to interpret than ever before. One computational analysis...
Jun, 01, 2005
Bringing Supercomputers to Life (Sciences)

Supercomputers open up new horizons, offering the possibility of discovering new ways to understand life’s complexity

Their very names sound like dinosaurs. Teracomputers. Petacomputers. These are, in fact, the dinosaurs of the digital world—monstrous, hungry and powerful. But unlike the extinct...
Oct, 01, 2006
Reverse-Engineering Transcriptional Networks

Finding the Master Regulators

A cell may change states several times in its lifetime—from a stem cell to a specialized cell, for example, or from a normal cell to a cancerous one. Each time this happens, a veritable army of...
Apr, 01, 2010
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