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Neuron Models: Simpler Is Better

Competition inspires model improvements

During the summer of 2009, the International Neuroinformatics Coordinating Facility in Stockholm dangled a nearly $10,000 cash prize in front of neuron modelers and challenged them to do better. And...
Jan, 01, 2010
Neurons Seek Their Own Solution

Computer models find that various ion channel arrangements can produce the same firing pattern

Each cell in our nervous system is an instrument in a complex symphony of electrophysiologic communication. A neuron’s signaling abilities arise from its array of ion channels—tunnels...
Jan, 01, 2007
The Dawn of Brain-Machine Interfaces

Brain implants are giving hope to the disabled and revolutionizing neuroscience

Matthew Nagle can move a cursor on a computer screen with only the power of his thoughts. It’s a remarkable feat for anyone, but especially momentous for Nagle, who is paralyzed from the neck...
Aug, 31, 2005
A Model Neuron
For patients suffering from nerve damage, neural regeneration is a faint hope. It rarely happens naturally, and attempts to coax new growth often fail. Researchers are trying to develop scaffolds to...
Apr, 01, 2009
Spaced out Neurons

A grant to develop software tools to analyze how neurons distribute themselves within the brain

Do neurons need personal space like people in an elevator? Are they influenced by their neighbors or do they randomly find a home in the brain? If the arrangement is patterned, what is the cause of...
neurons, software
Jun, 01, 2005
Behind the Connectome Commotion

Exploring the current state of connectomics--in the midst of hype

Connectomics is having a moment. Following on the heels of genomics, proteomics, transcriptomics, metabolomics, and microbiomics, the latest “omic” to seize the spotlight is generating...
brain, connectome
Jun, 20, 2013
Reverse Engineering the Brain
For a century, neuroscientists have dissected, traced, eavesdropped on, and are now compiling a seemingly endless cast of players in the nervous system. As we keep gathering more and more molecular...
neuron, reverse engineer
Apr, 01, 2009
Brain Chips

A new technique for measuring neuronal activity on a chip

Neurons are tough cells to study. There are a staggering number of them in most animals, and they are constantly talking with one another. One way to look at groups of neurons in real-time is to take...
Oct, 01, 2010
Smoking Addiction Explained

Putting neural and behavioral information together to model addiction

To non-smokers, the nasty-smelling habit is inexplicable. But now neurocomputational researchers have developed a hypothetical model to explain how nicotine produces addictive behavior. The first...
Apr, 01, 2006
Janelia Farm: Cultivating Scientists

Janelia farmers pursue novel, cross-disciplinary collaborations to work on long-term, unwieldy scientific problems difficult to tackle in a single laboratory

The folks at Howard Hughes Medical Institute who dreamed up Janelia Farm say it is as much a social innovation as a scientific one. “We are creating a different culture here,” says Gerald...
Jul, 01, 2006
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