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How Upper Level Ontologies Deal With Functions and Other Realizable Entities
Before categorizing things, you have to decide on the categories.  For material “things” (e.g., molecules, organs, etc.) or entities, the task is relatively straightforward. But...
Oct, 01, 2010
Tools to Understand the Federal Research Portfolio: From Ontologies to Topic Mapping

Computation helps evaluate the nature of the NIH research portfolio in ways that were previously very difficult.

What biomedical research does the federal government fund? How is it allocated across important diseases? Has that changed over time? Answering these questions at any level of detail is tougher than...
Jun, 08, 2012
Canonicity and Disease Ontologies
Ontologies provide biomedical researchers with an inventory of the universal features of reality across organisms, biomedical disciplines, and levels of granularity. In capturing what is universal,...
Jul, 01, 2009
Ontologies: A Way of Capturing and Representing Knowledge
Ontology, defined as "a theory of existence," has an important place in Western philosophy. It seeks to account for all phenomena in the universe.   In biomedical computation, however...
Jan, 01, 2006
Three New Centers
The National Institutes of Health Roadmap for Medical Research has recently completed the first stage of an ambitious program to expand the computational infrastructure and software tools needed to...
Jan, 01, 2006
Identifying and Overcoming Skepticism about Biomedical Computing

Modelers should take the lead.

Many collaborators 1        with whom modelers2 work have little or  no training in modeling3 and so it is natural that they may be cautious,...
Jun, 05, 2012
Semantic Publishing and Scientific Journals
Keeping up with the literature is a challenge for all scientists. But some researchers are making it easier by enhancing the usability and understanding of an article’s contents in a variety of...
Jul, 01, 2009
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Feb, 22, 2012
Journey to the NIH: Insights and Inspirations from the 2012 NCBC Showcase

Postdocs get a glance at the entire field and their first inside view of NIH grant-making

If he were a graduate student now, Francis Collins would be studying computational biology. That’s what the Director of the National Institutes of Health (NIH) told a rapt audience at the...
Feb, 19, 2013
NCBCs Take Stock and Look Forward: Fruitful Centers Face Sunset

From hardened software to scientific productivity, the NCBCs have changed the landscape for biomedical computing.  What will happen when their funding expires?

It has been eight years since the National Institutes of Health (NIH) funded the first National Centers for Biomedical Computing (NCBCs). With two or three years remaining in the program (...
ccb, i2b2, Magnet, na-mic, ncbo, NCIBI, Simbios
Oct, 19, 2012
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