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Visualization in Space and Time: Seamless Pipelines Now Available

Advances in visualization changing work flows for understanding molecular dynamics, tracking cell movements, and designing interventional procedures

The pathway from raw data to valuable visualization of molecules, cells or organs being simulated over time involves several potentially painstaking steps. Typically, researchers must generate a set...
atrial fibrillation, developmental biology, ePMV, patient-specific, visualization
Sep, 02, 2011
SimVascular to Simulate Cardiovascular Flow
On the computer screen, vessels throb realistically with each pump of the heart while the river of blood swirls and pools at curves and intersections. This is a simulation built with SimVascular...
Apr, 01, 2007
On Simulating Growth and Form

Simulations can teach us how young bodies and faces develop; how an artery compensates for decades of fatty plaque deposits by growing and thickening its walls; how tissue engineers can best coax endothelial cells to develop into organized sheets of skin for burn patients; and how cancerous tumors invade neighboring tissue.

For better or for worse, and on many levels, our tissues never stop growing and changing. While developing from childhood to old age, we grow not only bone, cartilage, fat, muscle and skin, but also...
Apr, 01, 2008
The Fate of Inhaled Particles
New computational model simulates how particles in the air get deposited in the lungs during breathing Depending on their nature, microscopic particles suspended in air—called aerosols—...
Apr, 01, 2009
The Physiome: A Mission Imperative

To understand biology—and provide appropriate medical care—scientists need to understand interactions across multiple scales. Hence the Physiome.

This is the reality of human biology: events span a 109 range in lengthscale (molecular to organismal) and a 1014 range in timescale (molecular movement to years). To understand this biology—...
Jun, 01, 2010
SimVascular User Profile: Alison Marsden, PhD

University of California, San Diego’s Alison Marsden uses SimVascular to do patient-specific modeling of blood flow for surgical applications.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Alison Marsden, PhD, an assistant professor of mechanical and aerospace engineering...
Oct, 01, 2009
Smart Embedded Devices: Here They Come

Machine learning for an artificial pancreas and deep brain stimulation

Embedded medical devices that both detect symptoms and treat them have existed for decades. Take, for example, the heart pacemaker. But a new generation of implants could soon emerge to do something...
diabetes, epilepsy, machine learning, pancreas, Parkinsons
Oct, 19, 2012
Continuum Mechanical Modeling of Biological Growth
Unlike most classical engineering materials, biological tissues can adapt to external stimuli by growing in volume: Skin grows in response to wounding; muscles grow in response to exercise; cancer...
Apr, 01, 2011
Meet the Skeptics: Why Some Doubt Biomedical Models - and What it Takes to Win Them Over

Disentangling the different types of skeptics and what modelers can learn from each.

What are the telltale signs of a modeling talk at a biology conference? Just look for the sighs, shifting, and eye-rolling in the audience, says Donald C. Bolser, PhD, professor of physiological...
Jun, 05, 2012
Untangling Integrative Analysis

How researchers are combining disparate data types and simulating systems that contain many different moving parts

13 years ago Markus Covert, PhD, read a New York Times article that changed his life.  The article quoted a prominent microbiologist who suggested that the ultimate test of one’s...
Feb, 16, 2013
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