It's an exhilarating time for genome-wide association studies
For the past few months it seemed you couldn’t open a journal without reading results of a new genome-wide association study. The results kept pouring in: four studies in April showing seven...
Oct, 01, 2007
The importance of developing and deploying tools for the quantitative clinician scientist
The word Om (or Aum) has many meanings in ancient Hindu philosophy, one of which is “that which contains all other sounds.” The meaning has relevance to the now commonly used suffix...
Jun, 01, 2010
A safe haven for asking fundamental, wide-ranging questions
In the summer, it can be hard to find a place to sit at the Santa Fe Institute. Much of the year, only about a dozen researchers make their home at the multidisciplinary research organization. But in...
Oct, 01, 2006
POINT/
NO: Grant applications for the development and maintenance of software and infrastructure should compete with basic research applications.
Biomedicine has a strong...
Jul, 01, 2009
POINT/
Less than meets the eye ...
Oct, 05, 2012
The Fall 2005 “Under the Hood” column discussed the curse of dimensionality—too many numerical components for each data point—and the curse of dataset sparsity—too few...
Oct, 01, 2010
During the final step of cell division, a ring of proteins pinches the cell in two—a process often likened to a purse string drawing shut. The analogy evokes a picture of thread-like proteins...
Apr, 01, 2008
The complexity and variability of aging itself, along with the fragmented nature of researchers’ current understanding of aging, call for tools that can help scientists dig through mounds of data to find often subtle connections.
Jeanne Louise Calment of Arles, France rode a bicycle until she was 100 years old. When she gave up smoking at age 117, her doctor suspected it was out of pride. (She couldn’t see well enough...
Apr, 01, 2008
Patients with schizophrenia and other psychotic disorders are known to have adverse brain changes, such as reduced volume—but it’s unclear what comes first, the disease or the abnormality...
Apr, 01, 2009
Hidden Markov models estimate DNA loop kinetics
The hidden Markov model—a statistical model used for decades in fields as diverse as speech recognition and climatology—has received an update and a new application. Researchers at the...
Apr, 01, 2007
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