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Privacy and Biomedical Research: Building a Trust Infrastructure

An exploration of data-driven and process-driven approaches to data privacy

Trust. It’s the basis of every patient/physician interaction: Shared personal health information is kept confidential and used only for the patient’s benefit. It’s a tradition that...
de-identification, differential privacy, HIPAA, k-anonymity, l-anonymity, privacy
Jan, 02, 2012
Computation Competitions Take Off!

Contests involving algorithms for protein structure prediction, natural language processing, and computer-aided disease detection are giving researchers a jolt of adrenalin and moving these fields forward

From all parts of the computational spectrum, researchers are duking it out: They are throwing their algorithms into the ring to see which one will out-perform all others on a particular task....
Jul, 01, 2006
Big Data Analytics In Biomedical Research

Can the complexities of biology be boiled down to Amazon.com-style recommendations?  The examples here suggest possible pathways to an intelligent healthcare system with big data at its core.

“We have recommendations for you,” announces the website Amazon.com each time a customer signs in.   This mega-retailer analyzes billions of customers’ purchases—nearly $...
Jan, 02, 2012
Share and Share Alike: A Proposed Set of Guidelines for Both Data and Software
A pair of challenges increasingly threaten the success of bioinformatics research: convincing biologists to share their data and convincing computational colleagues to share their code. Many of us...
Jul, 01, 2006
Bridging the Scientific Divide: Enabling Sharing through Biomedical Computing

How to share knowledge, data, tools, and computational resources in a sustainable manner

Once upon a time, a deep divide existed between scientists who did and those who did not have easy access to scientific content (journals, lectures, data), hardware (imaging devices, lab instruments...
sharing
Apr, 01, 2011
The Microbiome: Dealing with the Data Deluge

Bioinformatics and computational biology enable microbiome research

This past June, 200 members of the NIH-funded Human Microbiome Project (HMP) Consortium published a slew of papers offering fresh insights into the role microbial communities play in the human body...
JGI, microbiome
Oct, 22, 2012
Imaging Collections: How They're Stacking Up

As barriers to massive imaging collections fall, researchers can look at human systems in their entirety rather than in pieces

In the beginning there was the Visible Human. It broke new ground by gathering some 2,000 serial images from a death row inmate’s cadaver, and was the first time researchers had sectioned a...
Jul, 01, 2007
The Golden Age of Public Databases: Speeding Biomedical Discovery

Public databases impact not only how research is done but what kind of research is done in the first place.

The setting: a scientific conference in January 2008. The speaker, Bruce Ponder, MD, PhD, an oncology professor at Cambridge University, is describing a previously unknown link between a particular...
Oct, 01, 2008

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POPULAR ARTICLES

Big Data Analytics In Biomedical Research

Can the complexities of biology be boiled down to Amazon.com-style recommendations?  The examples here suggest possible pathways to an intelligent healthcare system with big data at its core.

01/02/12 by Katharine Miller

AlloPathFinder User Profile: Jung-Chi Liao

Columbia’s Jung-Chi Liao seeks pathways within proteins using AlloPathFinder, a Simbios tool he co-developed while at Stanford.

10/01/09 by Kristin Sainani, PhD, and Katharine Miller

More Than Fate: Computation Addresses Hot Topics in Stem Cell Research

Using computational models, researchers are gaining traction toward understanding what makes a stem cell a stem cell; how gene expression drives stem cell differentiation; why studying stem cell heterogeneity is important; and, ultimately, how stem cells control their fate.

04/01/10 by Katharine Miller

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