Protein design ascends to new heights
Synthetic biology moves beyond the whiteboard.
By computationally combining incomplete imaging information with bits and pieces of structural data from all sorts of different experiments, researchers have worked out the protein-by-protein structure of an important cellular assembly called the nuclear pore complex.
Central repository of information on genes and proteins requires participation by the scientific community
Computation can speed up the time it takes to find new binding partners for old drugs
Models of healthy and diseased lipid profiles could prove valuable diagnostically.
Using Rosetta@Home, a program that runs on the personal computers of 150,000 volunteers worldwide, David Baker’s team predicted the structure of a 112-amino-acid protein from scratch.
Working in silico, researchers hone in on candidate proteins worthy of laboratory work
Predicting protein localization
Researchers now have a tool for imaging the structures of biological molecules—and they are reaping the benefits big time.
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