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Scientific Discovery Through Video Games

"Fold-It" players find best protein conformations to fight cancer

When it comes to folding proteins, even modern supercomputers don’t always get things exactly right. Enter FoldIt, an online video game that harnesses the human brain’s natural pattern-...
Jan, 01, 2010
The Eyes Have It: Biomechanical Models Explore Disorders of the Eye

Biomechanical models contribute to a better understanding of both the normal and the diseased eye.

Squint, and you can almost  make out that bird soaring over the horizon. But determining whether it’s a hawk or a raven will be nearly impossible for someone with myopia, also known as...
Feb, 19, 2013
Breathing Life Into Paper
The edict that academics must “publish or perish” serves not merely to advance careers, but also to stress the importance of transmitting knowledge from scientist to scientist and...
Jan, 01, 2006
Visualizing Markov State Models Using MSMExplorer

A new application automates MSM visualization

An unfolded protein can move through thousands of intermediate structures (conformations) before finding its properly folded state. One approach to understanding this process involves simulating a...
Feb, 19, 2013
Sparks of Hope for a More Open Approach to Scientific Research and Publishing

Transparent peer review, replication studies, and journals of negative results all suggest change is on the horizon

As I was writing this editorial, I learned about yet another scientific paper being retracted. This time it was a genetics paper in Science, one of the hundreds of retractions that the blog...
errors, peer review, replication, scientific publication
Sep, 01, 2011
New Algorithm Finds Stories in Biomedical Literature

Algorithm joins related publications in a chain from start to finish

A good story ties up all the loose ends. A new data-mining tool takes a stab at doing the same. Dubbed storytelling, the algorithm may make it easier to unearth unexpected connections in the...
Jan, 01, 2007
Extra! Extra! Read All About It

Recent Publications About Biomedical Computing

The field of biomedical computation is increasingly seen as a hot topic worthy of coverage in publications other than Biomedical Computation Review.   In June 2005, The Scientist will publish a...
Jun, 01, 2005
Prototype to Release: Software Engineering for Scientific Software

Set objectives and follow through

Having engineered several scientific software applications for public consumption, the authors know from experience that the process offers unique challenges. Typically, the algorithms being...
Oct, 22, 2012
Janelia Farm: Cultivating Scientists

Janelia farmers pursue novel, cross-disciplinary collaborations to work on long-term, unwieldy scientific problems difficult to tackle in a single laboratory

The folks at Howard Hughes Medical Institute who dreamed up Janelia Farm say it is as much a social innovation as a scientific one. “We are creating a different culture here,” says Gerald...
Jul, 01, 2006
The Last Word
Dear Reader:   Welcome to the first issue of Biomedical Computation Review. With this quarterly publication, we hope to inspire and bring together scientists from the many fields that touch on...
Jun, 01, 2005
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