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Simbios: Bringing Biomedical Simulation to Your Fingertips

How Simbios' state-of-the-art software tools are contributing to high-impact biomedical research

Simbios began with a simple idea: that physics-based simulation of biological structures at all scales could benefit from a unified tool-building effort.   At the same time, the thinking went,...
Oct, 01, 2009
Infrastructure and Workforce Needs in Biomedical Informatics and Computational Biology
In science, there is a need to balance research in domain sciences and the infrastructure to support that research. Basic research mediated through peer review is understood to produce useful...
Jan, 01, 2007
Fulfilling the Promise of the NIH Roadmap Through National Engagement by the National Centers for Biomedical Computing (NCBC) and the CTSA Informatics
For major team-based Roadmap initiatives, National Institutes of Health (NIH) officials expect grantees to look beyond the focus of their individual projects to build bridges not only among funded...
Oct, 01, 2008
Parallel Computing on a Personal Computer
Anyone who has ever waited minutes, hours, or even days for software to complete a biomedical computation will be happy to hear that almost every personal computer is capable of better. Today,...
Jul, 01, 2008
Brain Chips

A new technique for measuring neuronal activity on a chip

Neurons are tough cells to study. There are a staggering number of them in most animals, and they are constantly talking with one another. One way to look at groups of neurons in real-time is to take...
Oct, 01, 2010
Lung Tumors Recap Developmental Patterns

Principal component analysis of gene expression signatures may help determine prognosis

Researchers have long speculated that many of the genetic programs responsible for rapid growth of tumors are also important for the growth that occurs during normal embryonic development.   Now...
Oct, 01, 2010
An insider’s view of biological structures
In March, Simbios released version 1.0 of the SimTK Simulation toolkit. A cornerstone of this release is Simbody, a new piece of the open-source SimTK Core toolkit for physics-based simulation....
Apr, 01, 2008
Simulation Simplified

Simbody introduces the concept of a “mobilizer,” which directly expresses a part’s movement, however complex, purely in relation to another part

Typically, researchers who simulate life in motion—from particles to people—start by describing the motion of each part of an object independently of the other parts. Additional equations...
Jan, 01, 2008
Putting Technology In Its Place
When you step on the gas pedal, you expect acceleration (and lots of it). Stomp on the brake to come safely to a stop in the rain. Finger the power-assisted steering wheel and the car obeys. Make a...
Oct, 01, 2009
Biocomputation Startups: Where Does Value Lie?

An opportunity and a challenge

When discussing biocomputation startups, there’s one thing people agree on: These days, they don’t generate much excitement among venture capitalists.   “In the 1990s, there...
Apr, 01, 2007
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Supported by the National
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