Several big-dollar initiatives received NIH funding in late 2010
In the current economic climate, every research dollar counts. Fortunately, when it comes to biomedical computing, not everyone has been left counting change. Several big-dollar initiatives received...
Apr, 01, 2011
Computers and human experts duke it out over who is better at diagnosing disease, interpreting images, or predicting protein structure
Dorothy Rosenthal tenses over her microscope, peering at the problematic nucleus on the Pap smear yet again. “It’s abnormal,” she decides, and then hesitates. “No, it’s...
Jul, 01, 2006
Simulations can teach us how young bodies and faces develop; how an artery compensates for decades of fatty plaque deposits by growing and thickening its walls; how tissue engineers can best coax endothelial cells to develop into organized sheets of skin for burn patients; and how cancerous tumors invade neighboring tissue.
For better or for worse, and on many levels, our tissues never stop growing and changing. While developing from childhood to old age, we grow not only bone, cartilage, fat, muscle and skin, but also...
Apr, 01, 2008
T-Rex in the Slow Lane
by Kristen Cobb
Tyrannosaurus rex is often pictured baring its teeth, crouching, and running swiftly after its prey, but these images are largely based on human fancy...
Jan, 01, 2006
There comes a tipping point in systems-biology studies of gene function where knowing some genes’ functions can, using a computational approach, help hone in on the functions of other genes....
Apr, 01, 2010
Mouse hair development patterns follow Turing's predictions
In the 1950s, computer science pioneer Alan Turing suggested an elegantly simple mechanism for how biological patterns such as scales, feathers, and hair might form. Now, more than fifty years later...
Apr, 01, 2007
POINT/
NO: Grant applications for the development and maintenance of software and infrastructure should compete with basic research applications.
Biomedicine has a strong...
Jul, 01, 2009
New approaches extend multiscale models to represent cellular mesoscales and bridge from molecular to cellular models
In an era of increasingly comprehensive molecular characterizations of living systems, computation has emerged as a key technology to facilitate integrative understanding of biological mechanisms....
Feb, 19, 2013
A myriad of environmental changes inspire only a handful of responses
Biologists’ favorite bacterium grows almost anywhere—from the human gut to the pounding surf. But E. coli’s remarkable adaptability apparently stems from being predictable rather...
Apr, 01, 2006
And people are starting to notice
In 1991, a prescient editorial in Nature by Harvard’s Walter Gilbert, PhD, (“Towards a paradigm shift in biology”) included these observations on the utility and impact of computing...
Apr, 01, 2006
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