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FOLLOW THE MONEY: Big Grants in Biomedical Computing

Several big-dollar initiatives received NIH funding in late 2010

In the current economic climate, every research dollar counts. Fortunately, when it comes to biomedical computing, not everyone has been left counting change. Several big-dollar initiatives received...
brain, immunity, network
Apr, 01, 2011
Visualizing Markov State Models Using MSMExplorer

A new application automates MSM visualization

An unfolded protein can move through thousands of intermediate structures (conformations) before finding its properly folded state. One approach to understanding this process involves simulating a...
Feb, 19, 2013
Visualization in Space and Time: Seamless Pipelines Now Available

Advances in visualization changing work flows for understanding molecular dynamics, tracking cell movements, and designing interventional procedures

The pathway from raw data to valuable visualization of molecules, cells or organs being simulated over time involves several potentially painstaking steps. Typically, researchers must generate a set...
atrial fibrillation, developmental biology, ePMV, patient-specific, visualization
Sep, 02, 2011
Human Versus Machine: Biomedical expertise meets computer automation

Computers and human experts duke it out over who is better at diagnosing disease, interpreting images, or predicting protein structure

Dorothy Rosenthal tenses over her microscope, peering at the problematic nucleus on the Pap smear yet again. “It’s abnormal,” she decides, and then hesitates. “No, it’s...
Jul, 01, 2006
From Sight to Insight: Visualization tools yield biomedical success stories
They're more than just pretty pictures adorning office walls and presentation slides. Beamed into operating room computer monitors, they're guiding the scalpels of brain surgeons. Dancing...
Jan, 01, 2012
The NCBC Centers: Incubators for the Next Generation of Science and Scientists

The NCBCs legacy of human capital

In this issue of Biomedical Computation Review, we feature a look at the NIH Roadmap National Centers for Biomedical Computing (NCBC) program. The NCBC program was a response to the recommendations...
Oct, 19, 2012
A Tipping Point for Function Prediction
There comes a tipping point in systems-biology studies of gene function where knowing some genes’ functions can, using a computational approach, help hone in on the functions of other genes....
Apr, 01, 2010
Scale-Free Networks in Contemporary Biology
A standard dictionary definition of a network is “an interconnected or interrelated chain, group, or system.” A cursory look at our surroundings shows that networks are ubiquitous. For...
Oct, 01, 2007
The Six Faces of E. Coli

A myriad of environmental changes inspire only a handful of responses

Biologists’ favorite bacterium grows almost anywhere—from the human gut to the pounding surf. But E. coli’s remarkable adaptability apparently stems from being predictable rather...
Apr, 01, 2006
Multiscale Modeling in Biomedical Research

New approaches extend multiscale models to represent cellular mesoscales and bridge from molecular to cellular models

In an era of increasingly comprehensive molecular characterizations of living systems, computation has emerged as a key technology to facilitate integrative understanding of biological mechanisms....
Feb, 19, 2013
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