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The Spontaneous Brain
When people sit peacefully at rest, doing and thinking nothing in particular, their brains still buzz merrily along. In scans called functional MRIs, they light up in characteristic patterns. No one...
Oct, 01, 2007
Diffusion Tensor Imaging Tractography: Revealing Connectivity in the Living Brain
One of the major obstacles to studying the human brain has always been gaining access. Until relatively recently, almost all of what we knew about the brain was obtained through post-mortem ...
Apr, 01, 2008
Where Tuberculosis Meets Computation: 10 Points of Intersection

Computation offers a window into a disease often described as a black box

The growing threats of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) are spurring worldwide interest in faster and more innovative research approaches, such as...
Jun, 06, 2012
Putting Heads Together
MICCAI 2007, the 10th International Conference on Medical Image Computing and Computer Assisted Intervention. What: MICCAI typically attracts over 600 world leading scientists, engineers and...
Oct, 01, 2007
Matters of Time: Tick Tock Go the Simulations

Computing using time steps -- a necessary approximation

Time flows like a continuous, steady river. And it moves forward—never back. These facts create inherent challenges for computer simulations of biological molecules in motion.   It would...
molecular dynamics, timesteps
Jun, 19, 2013
Continuum Mechanical Modeling of Biological Growth
Unlike most classical engineering materials, biological tissues can adapt to external stimuli by growing in volume: Skin grows in response to wounding; muscles grow in response to exercise; cancer...
Apr, 01, 2011
More Than Fate: Computation Addresses Hot Topics in Stem Cell Research

Using computational models, researchers are gaining traction toward understanding what makes a stem cell a stem cell; how gene expression drives stem cell differentiation; why studying stem cell heterogeneity is important; and, ultimately, how stem cells control their fate.

To the casual observer, stem cells offer the almost magical promise of—Voila!—turning into exactly the kind of cell needed to repair an injured spinal cord or replace a damaged organ. And...
stem cell
Apr, 01, 2010
The Top Ten Advances of the Last Decade & The Top Ten Challenges of the Next Decade

A recognition of biocomputing's successes and a prediction of what's to come

The last ten years have seen huge leaps in biomedical computing. We now have new ways to integrate and understand vast quantities of data; the capacity for multi-scale biological modeling; and a...
bioinformatics tools, biomedical computing, CAD, computational modeling, data mining, disease surveillance, dynamic modeling, education, eric jakobsson, function prediction, genetic association, genome annotation, in silico screening, medical informatics, neuromodeling, prosthetics, sequence alignment, structure prediction, systems biology, systems biomedicine, telemedicine, tomography
Jun, 01, 2005
NewsBytes: Winter 2005-2006
T-Rex in the Slow Lane by Kristen Cobb   Tyrannosaurus rex is often pictured baring its teeth, crouching, and running swiftly after its prey, but these images are largely based on human fancy...
Jan, 01, 2006
The Cell in 2010: A Modeling Odyssey

How cell-centered models are adding fundamental insights into our understanding of cell behaviors

The cell is like our financial system: Even if you have a diagram of all the complex interactions going on, you still cannot intuit how the whole system will react when perturbed. Indeed, the cell...
Apr, 01, 2010
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