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The Active Transport of Ideas

Researchers examine the connection between editorial boards of medical informatics and bioinformatics journals

How ideas spread gets at the very fabric of scholarly research and has been studied from many different angles.   Many studies examine person-to-person connectivity in social networks. Within a...
Jul, 01, 2007
Sparks of Hope for a More Open Approach to Scientific Research and Publishing

Transparent peer review, replication studies, and journals of negative results all suggest change is on the horizon

As I was writing this editorial, I learned about yet another scientific paper being retracted. This time it was a genetics paper in Science, one of the hundreds of retractions that the blog...
errors, peer review, replication, scientific publication
Sep, 01, 2011
The NCBC Centers: Incubators for the Next Generation of Science and Scientists

The NCBCs legacy of human capital

In this issue of Biomedical Computation Review, we feature a look at the NIH Roadmap National Centers for Biomedical Computing (NCBC) program. The NCBC program was a response to the recommendations...
Oct, 19, 2012
Chess, Thinking, Seeing, Jaggies and Chess... Again

I'd like to pay homage to James Burke and his inspiring PBS show Connections by taking you on my own short journey of connected ideas.

  The timeless game of chess has long been a grand challenge for artificial intelligence, with the number of possible games being much greater than the number of atoms in the universe. Baron...
Jan, 01, 2006
Open Solutions for Biomedical Research
What can open-source software do for biomedical research? Based on our experience at the National Alliance for Medical Image Computing (NA-MIC), we believe that open source software can be used very...
Mar, 01, 2009
Moon Shots in Biomedical Computation

As leaders and participants of an effort to build an infrastructure that enables biomedical computing on a broad basis, it is incumbent upon us to define clear and challenging goals that will dazzle the world

The world changed when Neil Armstrong set foot on the moon in 1969. Humans could survive outside the earth’s atmosphere! Science and engineering could achieve great things! And the nerds at the...
Jan, 01, 2008
Misconceptions of Time

Getting the molecular dynamics car out of the garage

For those who are not practitioners of dynamical simulation methods, such as molecular dynamics (MD), one of the biggest misconceptions relates to time. Specifically, the mismatch between the...
molecular dynamics simulations, time
Jun, 19, 2013
It’s Not What You Know, but What You Don’t Know…
Bioinformatics and computational biology have told us a lot about biology—primarily that we know so little. Advances have led to many more unanswered questions, suggesting we know less and less...
Oct, 01, 2007
When Does Computational Validation Trump Biological Validation?
Many a successful investigator working at the interface between molecular biology, genetics and computation will recognize the imperative to obtain biological validation for computational...
Jul, 01, 2008
Slaying Villains Outside The Ivory Tower

Lessons on leaving academia

Just over a year ago, I left academia. I had been in that realm for 25 years, working in musculoskeletal biomechanics and human movement analysis. It was a move that might have surprised anyone who...
academia, publishing
Jan, 02, 2012
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