Many a successful investigator working at the interface between molecular biology, genetics and computation will recognize the imperative to obtain biological validation for computational...
Jul, 01, 2008
Lessons on leaving academia
Just over a year ago, I left academia. I had been in that realm for 25 years, working in musculoskeletal biomechanics and human movement analysis. It was a move that might have surprised anyone who...
Jan, 02, 2012
A pair of challenges increasingly threaten the success of bioinformatics research: convincing biologists to share their data and convincing computational colleagues to share their code. Many of us...
Jul, 01, 2006
In science, there is a need to balance research in domain sciences and the infrastructure to support that research. Basic research mediated through peer review is understood to produce useful...
Jan, 01, 2007
The importance of developing and deploying tools for the quantitative clinician scientist
The word Om (or Aum) has many meanings in ancient Hindu philosophy, one of which is “that which contains all other sounds.” The meaning has relevance to the now commonly used suffix...
Jun, 01, 2010
Helping newcomers understand the lay of the land
As a program manager in biomedical computing and computational biology at the National Institutes of Health, I field many questions, particularly from new investigators. They ask questions like:...
Apr, 01, 2010
Today, the knowledge, experience and memory of clinicians or scientists function as the exclusive resource for distinguishing normal from abnormal brain images; identifying signatures or biomarkers...
Jul, 01, 2009
How to share knowledge, data, tools, and computational resources in a sustainable manner
Once upon a time, a deep divide existed between scientists who did and those who did not have easy access to scientific content (journals, lectures, data), hardware (imaging devices, lab instruments...
Apr, 01, 2011
Dear Reader,
In this eighteenth issue of Biomedical Computation Review (BCR), we bring you a special edition devoted to the work of the magazine’s publisher: the Simbios National Center...
Oct, 01, 2009
Modelers should take the lead.
Many collaborators 1 with whom modelers2 work have little or no training in modeling3 and so it is natural that they may be cautious,...
Jun, 05, 2012