Before categorizing things, you have to decide on the categories. For material “things” (e.g., molecules, organs, etc.) or entities, the task is relatively straightforward. But...
Oct, 01, 2010
Ontologies provide biomedical researchers with an inventory of the universal features of reality across organisms, biomedical disciplines, and levels of granularity. In capturing what is universal,...
Jul, 01, 2009
RunBot, already the world’s fastest bipedal robot, has now also learned to keep its balance when walking up ramps. “We have achieved a synthesis of different functionalities, between...
Oct, 01, 2007
One of our goals at Biomedical Computation Review is to create a sense of kinship among members of this very diverse community of researchers. This column provides reviews of some of the latest and...
Jun, 01, 2005
Models of healthy and diseased lipid profiles could prove valuable diagnostically.
When it comes to heart disease risk, “bad” and “good” cholesterol—also known as low density lipoproteins [LDL] and high density lipoproteins [HDL]—do not tell...
Oct, 01, 2008
New approaches extend multiscale models to represent cellular mesoscales and bridge from molecular to cellular models
In an era of increasingly comprehensive molecular characterizations of living systems, computation has emerged as a key technology to facilitate integrative understanding of biological mechanisms....
Feb, 19, 2013
Simulating molecular movement gives a more accurate view of binding sites.
If a picture’s worth a thousand words, then a motion picture, such as that provided by molecular dynamics (MD) simulations, must contain a wealth of information. It’s this potential...
Oct, 01, 2008
Using computational models, researchers are gaining traction toward understanding what makes a stem cell a stem cell; how gene expression drives stem cell differentiation; why studying stem cell heterogeneity is important; and, ultimately, how stem cells control their fate.
To the casual observer, stem cells offer the almost magical promise of—Voila!—turning into exactly the kind of cell needed to repair an injured spinal cord or replace a damaged organ. And...
Apr, 01, 2010
A newly created molecular computer works in human cells and offers the flexibility of a general-purpose circuit. The advance, described in Nature Biotechnology in May, brings closer the eventual...
Oct, 01, 2007
Katherine Holzbaur of Wake Forest University Medical School simulates the biomechanics of the upper limb.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Katherine Holzbaur, PhD, assistant professor of biomedical engineering at Wake Forest...
Oct, 01, 2009