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Implicit Representation of Biological Shapes and Forms
  Imaging, geometric modeling, representation and computing of shapes and forms are important components of modern computational biology. These processes apply across wide spectra of scales,...
Oct, 03, 2012
NAST User Profile: Li Niu, PhD

Li Niu of the University of Albany works with Simbios to understand an unusual RNA.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Li Niu, PhD, associate professor of chemistry at the University of Albany, SUNY found...
Oct, 01, 2009
Dimension Reduction and Manifold Learning: When Less Is More
The Fall 2005 “Under the Hood” column discussed the curse of dimensionality—too many numerical components for each data point—and the curse of dataset sparsity—too few...
Oct, 01, 2010
Protein Mechanica: Structural Modeling for the Experimentalist

Filling a gap in single molecule experimental work

Scientists sometimes find themselves up to their elbows in Styrofoam balls, pipe cleaners, and metal rods as they try to build models of the molecules they are studying. Now, they can exchange all...
Apr, 01, 2010
The Eyes Have It: Biomechanical Models Explore Disorders of the Eye

Biomechanical models contribute to a better understanding of both the normal and the diseased eye.

Squint, and you can almost  make out that bird soaring over the horizon. But determining whether it’s a hawk or a raven will be nearly impossible for someone with myopia, also known as...
Feb, 19, 2013
Profiles in Computer Science Courage Part I: Reflections on the rewards of plunging into biomedicine

Interviews with Leonidas Guibas, Ron Shamir, Michael Black, David Haussler, Daphne Koller, Erin Halperin, Gene Myers, Paul Groth and Bruce Donald

To a computer scientist, the fields of biology and medicine can seem like the vast Pacific Ocean, says Leonidas Guibas, PhD, professor of computer science at Stanford University. “You go to the...
Careers, computer science
Apr, 01, 2011
OpenSim User Profile: Katherine Holzbaur, PhD

Katherine Holzbaur of Wake Forest University Medical School simulates the biomechanics of the upper limb.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Katherine Holzbaur, PhD, assistant professor of biomedical engineering at Wake Forest...
Oct, 01, 2009
Solving the 3-D RNA Structure Puzzle with NAST
For proteins, structure information leads to an understanding of function. The same turns out to be true for ribozymes, ribosomal RNAs, and some other recently discovered RNAs. But mapping out that...
Mar, 01, 2009
Trajectory Optimization and Physical Realism

How adding jet packs to characters' hands can help optimize animations

An animated human figure seeking the optimal path from point A to point B typically relies on computationally expensive hard constraints that force the trajectories to be physically realistic. But...
Jun, 20, 2013
In the (Protein) Loop

LoopTK samples and visualizes many conformations of a protein loop to better understand loop movement

In the gaps between the tight coils and flattened sheets that comprise most protein structures, flexible loops wave and bend. When crystallized, these loops can appear fuzzy in an electron density...
Jul, 01, 2007
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