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Bacteria Prepare Themselves

Microbes react to environmental changes before they occur.

When we see dark clouds, we might grab an umbrella before heading outside.  We’ve long believed that showing such foresight requires a brain and complex information-processing capability...
Oct, 01, 2008
NewsBytes: Winter 2005-2006
T-Rex in the Slow Lane by Kristen Cobb   Tyrannosaurus rex is often pictured baring its teeth, crouching, and running swiftly after its prey, but these images are largely based on human fancy...
Jan, 01, 2006
Modeling Early Evolution
The fittest organisms survive and produce offspring, according to the Darwinian theory of natural selection. And the changes that make an organism fit happen at the molecular level: when genes mutate...
Oct, 01, 2007
Fulfilling the Promise of the NIH Roadmap Through National Engagement by the National Centers for Biomedical Computing (NCBC) and the CTSA Informatics
For major team-based Roadmap initiatives, National Institutes of Health (NIH) officials expect grantees to look beyond the focus of their individual projects to build bridges not only among funded...
Oct, 01, 2008
Packing It All In: Curricula for Biomedical Computing

Balancing Breadth and Depth

The last decade saw a proliferation of training programs at the intersection of life science and computation, with more than 60 new degree and certificate programs launched in the United States alone...
Sep, 01, 2005
Successful Collaborations: Helping biomedicine and computation play well together

Collaborations are a fact of life for interdisciplinary fields like biomedical computing, and social scientists can help researchers understand how to make them more productive

Social scientists who study science have noticed a trend: More and more researchers are collaborating. Over the last twenty years, the number of co-authored papers has increased in every scientific...
Jul, 01, 2008
Life in Motion: Simulation from Particles to People

Computational simulations of life in motion at every scale—molecular, cellular, tissue-level, and whole organism—are boosting our understanding of the role mechanics plays in controlling life.

From atoms and molecules to insects, dinosaurs, and humans, computational researchers are finding that much of life can be understood in mechanical terms. Indeed, the machines of life are...
Jan, 01, 2008
The Golden Age of Public Databases: Speeding Biomedical Discovery

Public databases impact not only how research is done but what kind of research is done in the first place.

The setting: a scientific conference in January 2008. The speaker, Bruce Ponder, MD, PhD, an oncology professor at Cambridge University, is describing a previously unknown link between a particular...
Oct, 01, 2008
The Epigenome: A New View Into the Book of Life

There is growing recognition that epigenetics may be just as important as genetics in human health and disease.

In the early 19th century, Jean-Baptiste Lamarck explained evolution as the inheritance of acquired traits; he believed that changes due to behaviors and exposures in one generation could be passed...
Jun, 01, 2010
Identifying and Overcoming Skepticism about Biomedical Computing

Modelers should take the lead.

Many collaborators 1        with whom modelers2 work have little or  no training in modeling3 and so it is natural that they may be cautious,...
Jun, 05, 2012
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