LoopTK samples and visualizes many conformations of a protein loop to better understand loop movement
In the gaps between the tight coils and flattened sheets that comprise most protein structures, flexible loops wave and bend. When crystallized, these loops can appear fuzzy in an electron density...
Jul, 01, 2007
Confidence boost for modelers
It’s often said that all models are wrong, but some are useful. And one model that certainly falls in the “useful” category is the human lower-limb model that Scott Delp published...
Jun, 01, 2010
Using molecular dynamics (MD) software, scientists can simulate molecular movement to study biological phenomena that currently cannot be observed experimentally.
But the value of MD...
Jul, 01, 2009
AMOEBA's polarizable force field now integrated with OpenMM
Many have long hoped that molecular dynamics calculations—the computation of how molecules move and interact with other molecules—would revolutionize the world of synthetic chemistry,...
Sep, 01, 2011
In March, Simbios released version 1.0 of the SimTK Simulation toolkit. A cornerstone of this release is Simbody, a new piece of the open-source SimTK Core toolkit for physics-based simulation....
Apr, 01, 2008
There are numerous musculoskeletal modeling methods available to make predictions of muscle and joint contact forces. While such predictions can help improve treatments for movement-related disorders...
Jan, 02, 2012
Assuring accuracy and efficiency
In simulations of human activities such as running, hundreds of individual musculotendon models turn on and off to swing the arms and legs. Naturally, these simulations can only be as accurate and...
Jun, 19, 2013
Students, not faculty, are the ones in charge
Outwardly, the Biomedical Computation at Stanford (BCATS) conference resembles other academic conferences: Researchers converge to hear about the latest developments in their field and to...
Jan, 01, 2008
New release improves both GUI and API
OpenSim, the neuromuscular modeling and simulation software, is now available in a new digit: 3.0. The change (up from 2.4) reflects significant improvements that make this open source tool more...
Oct, 19, 2012
Visualizing a single, public body
The mesh body of a human form floats over the Brooklyn Bridge. Dots of color, embedded with video testimonials, share the collective health problems of 9/11 survivors. In this incarnation,...
Jul, 01, 2008