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Three New Centers
The National Institutes of Health Roadmap for Medical Research has recently completed the first stage of an ambitious program to expand the computational infrastructure and software tools needed to...
Jan, 01, 2006
Bringing the Fruits of Computation to Bear on Human Health: It’s a Tough Job but the NIH Has to Do It
The National Institutes of Health are on a mission: To understand and tackle the problems of human health. To make that daunting problem approachable, 15 of the 20 institutes divvy up human health...
Oct, 05, 2012
The Physiome: A Mission Imperative

To understand biology—and provide appropriate medical care—scientists need to understand interactions across multiple scales. Hence the Physiome.

This is the reality of human biology: events span a 109 range in lengthscale (molecular to organismal) and a 1014 range in timescale (molecular movement to years). To understand this biology—...
Jun, 01, 2010
Grand Challenge Competition Provides Rich Data Set to Improve Joint Contact Force Predictions
There are numerous musculoskeletal modeling methods available to make predictions of muscle and joint contact forces. While such predictions can help improve treatments for movement-related disorders...
knee
Jan, 02, 2012
Computational Biomechanics: Making Strides Toward Patient Care

Moving from intuition to evidence-based intervention

To understand how muscles contract and joints flex, researchers have dissected cadavers and experimented with animals. They can describe how bones, muscles, and tendons connect in a complicated...
Jan, 01, 2007
CAMPAIGN: Expanding the Universe for Clustering Algorithms

Speedups produced by a C++ library of Clustering Algorithms for Massively Parallel Architectures Including GPU Nodes

GenBank, a repository for storing biological sequences, currently contains some 124 billion base pairs and is doubling in size every 18 months.1 Though not a huge number compared to the billion...
Apr, 01, 2011
On Your Mark, Get Set, Build Infrastructure: The NCBC Launch

The first four National Centers for Biomedical Computing take off

WHY NATIONAL CENTERS? Four National Centers for Biomedical Computing were launched by the NIH in 2004 with $20 million in funding for each center over five years. The reason: We need to make...
Jun, 01, 2005
NCBCs Take Stock and Look Forward: Fruitful Centers Face Sunset

From hardened software to scientific productivity, the NCBCs have changed the landscape for biomedical computing.  What will happen when their funding expires?

It has been eight years since the National Institutes of Health (NIH) funded the first National Centers for Biomedical Computing (NCBCs). With two or three years remaining in the program (...
ccb, i2b2, Magnet, na-mic, ncbo, NCIBI, Simbios
Oct, 19, 2012
Successful Collaborations: Helping biomedicine and computation play well together

Collaborations are a fact of life for interdisciplinary fields like biomedical computing, and social scientists can help researchers understand how to make them more productive

Social scientists who study science have noticed a trend: More and more researchers are collaborating. Over the last twenty years, the number of co-authored papers has increased in every scientific...
Jul, 01, 2008
Structural Genomics: Exploring the 3D Protein Landscape

How increased coverage of the structure space is transforming the field of biology

When the human genome was completely sequenced in 2003, researchers were already pondering how biomedicine could make use of it.  One hope was that the sequences would lead to a greater...
Jan, 01, 2010
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