Filling a gap in single molecule experimental work
Scientists sometimes find themselves up to their elbows in Styrofoam balls, pipe cleaners, and metal rods as they try to build models of the molecules they are studying. Now, they can exchange all...
Apr, 01, 2010
Even when we simply stand still on two feet, our brains communicate with our muscles—firing them appropriately to keep us upright against gravity. So when scientists simulate simple or complex...
Jun, 06, 2012
LoopTK samples and visualizes many conformations of a protein loop to better understand loop movement
In the gaps between the tight coils and flattened sheets that comprise most protein structures, flexible loops wave and bend. When crystallized, these loops can appear fuzzy in an electron density...
Jul, 01, 2007
Confidence boost for modelers
It’s often said that all models are wrong, but some are useful. And one model that certainly falls in the “useful” category is the human lower-limb model that Scott Delp published...
Jun, 01, 2010
AMOEBA's polarizable force field now integrated with OpenMM
Many have long hoped that molecular dynamics calculations—the computation of how molecules move and interact with other molecules—would revolutionize the world of synthetic chemistry,...
Sep, 01, 2011
For proteins, structure information leads to an understanding of function. The same turns out to be true for ribozymes, ribosomal RNAs, and some other recently discovered RNAs. But mapping out that...
Mar, 01, 2009
Students, not faculty, are the ones in charge
Outwardly, the Biomedical Computation at Stanford (BCATS) conference resembles other academic conferences: Researchers converge to hear about the latest developments in their field and to...
Jan, 01, 2008
There are numerous musculoskeletal modeling methods available to make predictions of muscle and joint contact forces. While such predictions can help improve treatments for movement-related disorders...
Jan, 02, 2012
New release improves both GUI and API
OpenSim, the neuromuscular modeling and simulation software, is now available in a new digit: 3.0. The change (up from 2.4) reflects significant improvements that make this open source tool more...
Oct, 19, 2012
Dear Reader,
In this eighteenth issue of Biomedical Computation Review (BCR), we bring you a special edition devoted to the work of the magazine’s publisher: the Simbios National Center...
Oct, 01, 2009