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OpenSim User Profile: B.J. Fregly, PhD

University of Florida’s B.J. Fregly hopes to use OpenSim to simulate the knee.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   B.J. Fregly, PhD, associate professor of mechanical and aerospace engineering and of...
Oct, 01, 2009
Hot Bodies a Lure for Unseen Specks

Computing airflow dynamics

We can’t see them, but tiny particles—dust, pollen, microbes, and the like—swirl around us in complicated, turbulent pathways. New numerical simulations suggest that, at least in...
Jun, 01, 2010
Visualization in Space and Time: Seamless Pipelines Now Available

Advances in visualization changing work flows for understanding molecular dynamics, tracking cell movements, and designing interventional procedures

The pathway from raw data to valuable visualization of molecules, cells or organs being simulated over time involves several potentially painstaking steps. Typically, researchers must generate a set...
atrial fibrillation, developmental biology, ePMV, patient-specific, visualization
Sep, 02, 2011
Human Versus Machine: Biomedical expertise meets computer automation

Computers and human experts duke it out over who is better at diagnosing disease, interpreting images, or predicting protein structure

Dorothy Rosenthal tenses over her microscope, peering at the problematic nucleus on the Pap smear yet again. “It’s abnormal,” she decides, and then hesitates. “No, it’s...
Jul, 01, 2006
Conducting Medical Research from Electronic Health Records

Using natural language processing to find necessary samples

To discover links between genes and disease, researchers typically recruit individual patients with and without the disease of interest; have them sign consent forms; take their medical histories;...
Jan, 01, 2010
Ramping Up to Multiscale: Taking Biomedical Modeling to a New Level

Multi-scale modeling is now at what might be called its gestational stage

For centuries, mathematics has been an indispensable ally of the physical sciences and engineering. Planes fly and telephones work because engineers know how to simplify physical systems into...
Apr, 01, 2006
Learning about cells by examining how they scatter light

Looking inside the cell without opening it

When light hits an obstacle, its scattering pattern reveals information regarding the internal structure of the obstacle. If that obstacle is a cell, the scattering pattern might indicate whether the...
Jun, 01, 2005
Simulating Cells in Context: Bringing Mechanics Into Play
Like humans, cells are affected by their physical environment, their neighbors, the context in which they exist. Much research has focused on the chemical signals that control cell behavior. But...
developmental biology
Sep, 01, 2011
Synchronizing Cells

Synthetic biologists explain cell behaviors while desinging new ones

Without synchronized clocks—whether embedded in our body’s cells or programmed into our desktop computers—any kind of coordinated activity is impossible. So after synthetic...
Apr, 01, 2010
Efficiently Evaluating Mathematical Expressions with OpenCL Code

A unique opportunity to build both flexibility and high performance into a piece of software.

OpenCL is a cross-platform language for doing general purpose computation on graphics processing units (GPUs) and other massively parallel architectures. One of its most interesting features is the...
Apr, 01, 2010
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