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Different But Equal
Kids often claim they are just as smart—if not smarter—than their parents. Childish nonsense? Perhaps not, according to a recent study. It turns out that young children’s brains are...
Oct, 01, 2009
Computing the Ravages of Time: Using Algorithms To Tackle Alzheimer’s Disease

Biomarker research, genetics, and imaging are all coming into play

In 1906, at a small medical meeting in Tübingen, Germany, physician Alois Alzheimer gave a now-famous presentation about a puzzling patient. At age 51, Auguste D.’s memory was failing...
Oct, 01, 2007
Computer Vision that Mimics Human Vision

Computer vision program rivals the human ability to rapidly recognize objects in a complex picture

Our brains can recognize most of the things we pass on an evening stroll: Cars, buildings, trees, and people all register even at a great distance or from an odd angle. Now, a new computer vision...
Jul, 01, 2007
A Vision of Computational Anatomy
Today, the knowledge, experience and memory of clinicians or scientists function as the exclusive resource for distinguishing normal from abnormal brain images; identifying signatures or biomarkers...
Jul, 01, 2009
Implicit Representation of Biological Shapes and Forms
  Imaging, geometric modeling, representation and computing of shapes and forms are important components of modern computational biology. These processes apply across wide spectra of scales,...
Oct, 03, 2012
Parkinson’s Culprit Modeled

A computational model of alpha-synuclein as it aggregates

Under a microscope, the curious protein clumps that dot the brains of Parkinson’s patients stick out like the culprits they are. But no one has yet caught the protein—alpha-synuclein...
Jul, 01, 2007
Bacteria Prepare Themselves

Microbes react to environmental changes before they occur.

When we see dark clouds, we might grab an umbrella before heading outside.  We’ve long believed that showing such foresight requires a brain and complex information-processing capability...
Oct, 01, 2008
Bringing Supercomputers to Life (Sciences)

Supercomputers open up new horizons, offering the possibility of discovering new ways to understand life’s complexity

Their very names sound like dinosaurs. Teracomputers. Petacomputers. These are, in fact, the dinosaurs of the digital world—monstrous, hungry and powerful. But unlike the extinct...
Oct, 01, 2006
On Your Mark, Get Set, Build Infrastructure: The NCBC Launch

The first four National Centers for Biomedical Computing take off

WHY NATIONAL CENTERS? Four National Centers for Biomedical Computing were launched by the NIH in 2004 with $20 million in funding for each center over five years. The reason: We need to make...
Jun, 01, 2005
The Epigenome: A New View Into the Book of Life

There is growing recognition that epigenetics may be just as important as genetics in human health and disease.

In the early 19th century, Jean-Baptiste Lamarck explained evolution as the inheritance of acquired traits; he believed that changes due to behaviors and exposures in one generation could be passed...
Jun, 01, 2010
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