About this issue of Biomedical Computation Review
One of the main goals of this magazine is to create and foster a sense of community among the diverse disciplines that make up biomedical computation (hence our tagline: diverse disciplines, one...
Sep, 01, 2005
The edict that academics must “publish or perish” serves not merely to advance careers, but also to stress the importance of transmitting knowledge from scientist to scientist and...
Jan, 01, 2006
Simplified model catches essential details of how DNA complements find their matches
Until now, scientists have known little about how complementary single strands of DNA court one another before binding to form the classical double helix. But now, molecular dynamics simulations have...
Jan, 01, 2010
Bioinformatics and computational biology enable microbiome research
This past June, 200 members of the NIH-funded Human Microbiome Project (HMP) Consortium published a slew of papers offering fresh insights into the role microbial communities play in the human body...
Oct, 22, 2012
For proteins, structure information leads to an understanding of function. The same turns out to be true for ribozymes, ribosomal RNAs, and some other recently discovered RNAs. But mapping out that...
Mar, 01, 2009
An explanation of geometric constraints in computational biomechanics
Suppose 20 friends live in the same city and want to meet for dinner. They should be able to identify a unique spot that minimizes the squared distance everyone needs to travel by taking the...
Jan, 02, 2012
Now, with just a few mouse clicks, anyone with a computer and an Internet connection can create graphic images of RNA molecules (using ToRNADo) or generate the ion environments that surround these...
Jan, 01, 2007
A debate
Say you are performing biomolecular investigations that are extremely compute intensive. You have a finite amount of money and time. You could get (1) a supercomputer (fast custom CPUs and high-speed...
Oct, 01, 2009
POINT/
NO: Grant applications for the development and maintenance of software and infrastructure should compete with basic research applications.
Biomedicine has a strong...
Jul, 01, 2009
From hardened software to scientific productivity, the NCBCs have changed the landscape for biomedical computing. What will happen when their funding expires?
It has been eight years since the National Institutes of Health (NIH) funded the first National Centers for Biomedical Computing (NCBCs). With two or three years remaining in the program (...
Oct, 19, 2012