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Molecular Biology Wikis Launched

Central repository of information on genes and proteins requires participation by the scientific community

If you build it, will they come? That’s the question on everyone’s mind after the launch of two pioneering initiatives in community annotation: WikiProteins and Gene Wiki, announced,...
Oct, 01, 2008
Dock This: In Silico Drug Design Feeds Drug Development

As algorithms evolve, computing power explodes, and scientists solve a greater number of 3-D protein structures, computer-aided design has the potential to dramatically cut the cost and time of drug discovery

Once upon a time, not long ago, HIV/AIDS was a scourge, killing anyone who contracted the deadly virus. Now, many people are living with the disease, which they control with drugs initially developed...
Jul, 01, 2007
Welcome Back

About this issue of Biomedical Computation Review

One of the main goals of this magazine is to create and foster a sense of community among the diverse disciplines that make up biomedical computation (hence our tagline: diverse disciplines, one...
Sep, 01, 2005
Mining Biomedical Literature: Using Computers to Extract Knowledge Nuggets

Researchers are not simply retrieving and repackaging what is already known, but are also deriving new knowledge by discovering connections that were previously unnoticed.

Not long ago, reading biomedical literature involved hours in the library combing through rows of dusty periodicals—not to mention pocketfuls of change for the copy machine. Now, although the...
Jul, 01, 2008
Scientific Discovery Through Video Games

"Fold-It" players find best protein conformations to fight cancer

When it comes to folding proteins, even modern supercomputers don’t always get things exactly right. Enter FoldIt, an online video game that harnesses the human brain’s natural pattern-...
Jan, 01, 2010
Behind the Connectome Commotion

Exploring the current state of connectomics--in the midst of hype

Connectomics is having a moment. Following on the heels of genomics, proteomics, transcriptomics, metabolomics, and microbiomics, the latest “omic” to seize the spotlight is generating...
brain, connectome
Jun, 20, 2013
The Top Ten Advances of the Last Decade & The Top Ten Challenges of the Next Decade

A recognition of biocomputing's successes and a prediction of what's to come

The last ten years have seen huge leaps in biomedical computing. We now have new ways to integrate and understand vast quantities of data; the capacity for multi-scale biological modeling; and a...
bioinformatics tools, biomedical computing, CAD, computational modeling, data mining, disease surveillance, dynamic modeling, education, eric jakobsson, function prediction, genetic association, genome annotation, in silico screening, medical informatics, neuromodeling, prosthetics, sequence alignment, structure prediction, systems biology, systems biomedicine, telemedicine, tomography
Jun, 01, 2005
Clinical Decision Support: Providing Quality Healthcare with Help from a Computer
In a classic cartoon, a physician offers a second opinion from his computer.  The patient looks horrified: How absurd to think that a computer could have better judgment than a human doctor! But...
Jan, 01, 2010
Point/Counterpoint: Should there be a separate funding mechanism for the development and maintenance of software and infrastructure?
  POINT/   NO:  Grant applications for the development and maintenance of software and infrastructure should compete with basic research applications. Biomedicine has a strong...
Jul, 01, 2009
Profiles in Computer Science Courage Part I: Reflections on the rewards of plunging into biomedicine

Interviews with Leonidas Guibas, Ron Shamir, Michael Black, David Haussler, Daphne Koller, Erin Halperin, Gene Myers, Paul Groth and Bruce Donald

To a computer scientist, the fields of biology and medicine can seem like the vast Pacific Ocean, says Leonidas Guibas, PhD, professor of computer science at Stanford University. “You go to the...
Careers, computer science
Apr, 01, 2011
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