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From Sight to Insight: Visualization tools yield biomedical success stories
They're more than just pretty pictures adorning office walls and presentation slides. Beamed into operating room computer monitors, they're guiding the scalpels of brain surgeons. Dancing...
Jan, 01, 2012
Assembling The Aging Puzzle: Computation Helps Connect the Pieces

The complexity and variability of aging itself, along with the fragmented nature of researchers’ current understanding of aging, call for tools that can help scientists dig through mounds of data to find often subtle connections.

Jeanne Louise Calment of Arles, France rode a bicycle until she was 100 years old. When she gave up smoking at age 117, her doctor suspected it was out of pride. (She couldn’t see well enough...
Apr, 01, 2008
Computational Biology Catches the Flu: Modeling the bug, the host, the world
The flu virus is an evolutionary marvel. Teams of experts design an appropriate flu vaccine annually just to keep up with the microbe’s ability to evade the human immune system. Multiple...
Jul, 01, 2006
Follow the Money: Big Grants in Biomedical Computing

The clear winner: Big Data

 

Several biomedical computing projects received big money in the fall of 2012. If there’s one clear winner, it’s “Big Data”: three of the grants focus on building new...
Feb, 19, 2013
The Microbiome: Dealing with the Data Deluge

Bioinformatics and computational biology enable microbiome research

This past June, 200 members of the NIH-funded Human Microbiome Project (HMP) Consortium published a slew of papers offering fresh insights into the role microbial communities play in the human body...
JGI, microbiome
Oct, 22, 2012
New Algorithm Finds Stories in Biomedical Literature

Algorithm joins related publications in a chain from start to finish

A good story ties up all the loose ends. A new data-mining tool takes a stab at doing the same. Dubbed storytelling, the algorithm may make it easier to unearth unexpected connections in the...
Jan, 01, 2007
Structural Genomics: Exploring the 3D Protein Landscape

How increased coverage of the structure space is transforming the field of biology

When the human genome was completely sequenced in 2003, researchers were already pondering how biomedicine could make use of it.  One hope was that the sequences would lead to a greater...
Jan, 01, 2010
When Does Computational Validation Trump Biological Validation?
Many a successful investigator working at the interface between molecular biology, genetics and computation will recognize the imperative to obtain biological validation for computational...
Jul, 01, 2008
The Physiome: Standardizing the Physiome

A closer look at the curation of models discussed in The Physiome: A Mission Imperative

Multi-scale quantitative models need to be validated and reproducible if they are to be useful for clinical workflows, says Hunter. The Physiome infrastructure developed by Hunter, Dr Poul Nielsen...
Jun, 01, 2010
Bayesian Networks: A Quick Intro
Advances in technology have brought to molecular biology datasets that are bigger, more sophisticated, and, unfortunately, more difficult to interpret than ever before. One computational analysis...
Jun, 01, 2005
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