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Infrastructure and Workforce Needs in Biomedical Informatics and Computational Biology
In science, there is a need to balance research in domain sciences and the infrastructure to support that research. Basic research mediated through peer review is understood to produce useful...
Jan, 01, 2007
Putting Heads Together

Upcoming biocomputing conferences

The 6th Annual International Conference on Computational Systems Bioinformatics (CSB2007) coordinated by the Life Sciences Society. WHAT: This conference is designed for any scientist interested in...
Jul, 01, 2007
Where Tuberculosis Meets Computation: 10 Points of Intersection

Computation offers a window into a disease often described as a black box

The growing threats of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) are spurring worldwide interest in faster and more innovative research approaches, such as...
Jun, 06, 2012
Taking the leap: from single genes to the molecular choreography of the cell
The Human Genome Project has spurred extraordinary developments in our ability to characterize cellular systems in high-throughput fashion. Polymorphism, methylation, gene expression, and proteomics...
Apr, 01, 2008
Predicting Protein Complexes

A combination of genomics data and molecular dynamics modeling is sufficient to predict protein complex structure

The zone where two proteins interact presents a possible target for drug design. But identifying possible drugs requires a detailed understanding of the interface between the proteins. Computer...
Apr, 01, 2010
Mining Biomedical Literature: Using Computers to Extract Knowledge Nuggets

Researchers are not simply retrieving and repackaging what is already known, but are also deriving new knowledge by discovering connections that were previously unnoticed.

Not long ago, reading biomedical literature involved hours in the library combing through rows of dusty periodicals—not to mention pocketfuls of change for the copy machine. Now, although the...
Jul, 01, 2008
Santa Fe Institute: Addressing Complexity

A safe haven for asking fundamental, wide-ranging questions

In the summer, it can be hard to find a place to sit at the Santa Fe Institute. Much of the year, only about a dozen researchers make their home at the multidisciplinary research organization. But in...
Oct, 01, 2006
Spit Diagnostics

The Salivary Proteome Knowledge Base

If spit could talk, it might tell us whether we’re sick or healthy.   According to David Wong, DMD, DMSc—professor and associate dean of research at the School of Dentistry at the...
Jun, 01, 2005
The Microbiome: Dealing with the Data Deluge

Bioinformatics and computational biology enable microbiome research

This past June, 200 members of the NIH-funded Human Microbiome Project (HMP) Consortium published a slew of papers offering fresh insights into the role microbial communities play in the human body...
JGI, microbiome
Oct, 22, 2012
Big Data Analytics In Biomedical Research

Can the complexities of biology be boiled down to Amazon.com-style recommendations?  The examples here suggest possible pathways to an intelligent healthcare system with big data at its core.

“We have recommendations for you,” announces the website Amazon.com each time a customer signs in.   This mega-retailer analyzes billions of customers’ purchases—nearly $...
Jan, 02, 2012
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