In the world of molecular dynamics (MD), researchers often need to analyze and extract meaningful results from millions of conformations. Existing software for accomplishing this task focuses on...
Oct, 01, 2009
A new media artwork explores novel ways to represent and intuitively understand nature in the metagenomic era
What’s it like to be immersed in a dataset of millions of DNA sequences? Audiences of ATLAS in silico—a new media artwork that explores novel ways to represent and intuitively understand...
Oct, 01, 2008
How Simbios' state-of-the-art software tools are contributing to high-impact biomedical research
Simbios began with a simple idea: that physics-based simulation of biological structures at all scales could benefit from a
unified tool-building effort.
At the same time, the thinking went,...
Oct, 01, 2009
A grant to develop software tools to analyze how neurons distribute themselves within the brain
Do neurons need personal space like people in an elevator? Are they influenced by their neighbors or do they randomly find a home in the brain? If the arrangement is patterned, what is the cause of...
Jun, 01, 2005
While science educators actively debate the relative merits of teaching natural science in an integrated fashion, some authors are writing texts that will make it happen. Philip Nelson’s book,...
Jun, 01, 2005
A debate
Say you are performing biomolecular investigations that are extremely compute intensive. You have a finite amount of money and time. You could get (1) a supercomputer (fast custom CPUs and high-speed...
Oct, 01, 2009
As algorithms evolve, computing power explodes, and scientists solve a greater number of 3-D protein structures, computer-aided design has the potential to dramatically cut the cost and time of drug discovery
Once upon a time, not long ago, HIV/AIDS was a scourge, killing anyone who contracted the deadly virus. Now, many people are living with the disease, which they control with drugs initially developed...
Jul, 01, 2007
To understand biology—and provide appropriate medical care—scientists need to understand interactions across multiple scales. Hence the Physiome.
This is the reality of human biology: events span a 109 range in lengthscale (molecular to organismal) and a 1014 range in timescale (molecular movement to years). To understand this biology—...
Jun, 01, 2010
The study of HIV evolution is not only critical to fighting the virus; it has also driven advances in the computational tools used to study evolution in general.
When Darwin published On the Origin of Species in 1859, it would be decades before HIV would jump from monkeys to humans and set off a devastating worldwide pandemic. But evolution is at the heart of...
Jul, 01, 2009
They're more than just pretty pictures adorning office walls and presentation slides. Beamed into operating room computer monitors, they're guiding the scalpels of brain surgeons. Dancing...
Jan, 01, 2012