Disentangling the different types of skeptics and what modelers can learn from each.
What are the telltale signs of a modeling talk at a biology conference? Just look for the sighs, shifting, and eye-rolling in the audience, says Donald C. Bolser, PhD, professor of physiological...
Jun, 05, 2012
An elegant new model of balance control suggests the brain only cares about one thing: the body’s center of mass.
Bumped from behind, a person may step forward to avoid falling. Perhaps her arms fly out as well. To the untrained eye, these movements seem like the result of the brain controlling individual nerve...
Jan, 01, 2008
Jill Higginson at the University of Delaware uses OpenSim to study stroke.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Jill Higginson, PhD, assistant professor of mechanical engineering at the University...
Oct, 01, 2009
Multi-scale modeling is now at what might be called its gestational stage
For centuries, mathematics has been an indispensable ally of the physical sciences and engineering. Planes fly and telephones work because engineers know how to simplify physical systems into...
Apr, 01, 2006
Computation offers a window into a disease often described as a black box
The growing threats of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) are spurring worldwide interest in faster and more innovative research approaches, such as...
Jun, 06, 2012
Atomistic simulations have the potential to elucidate the molecular basis of biological processes such as protein misfolding in Alzheimer’s disease or the conformational changes that drive...
Jan, 01, 2010
A new application automates MSM visualization
An unfolded protein can move through thousands of intermediate structures (conformations) before finding its properly folded state. One approach to understanding this process involves simulating a...
Feb, 19, 2013
Simbios broadened University of Virginia’s Silvia Blemker’s horizons; and OpenSim is helping her understand hamstring injuries in sprinters.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Silvia Blemker, PhD, has deep roots in Simbios. As a Stanford graduate student, she...
Oct, 01, 2009
Simulations can teach us how young bodies and faces develop; how an artery compensates for decades of fatty plaque deposits by growing and thickening its walls; how tissue engineers can best coax endothelial cells to develop into organized sheets of skin for burn patients; and how cancerous tumors invade neighboring tissue.
For better or for worse, and on many levels, our tissues never stop growing and changing. While developing from childhood to old age, we grow not only bone, cartilage, fat, muscle and skin, but also...
Apr, 01, 2008
Modeling what triggers heart cells to relax
When a heart beats, millions of muscle cells contract in unison to pump blood to the body; then they relax, allowing the heart to refill. Though scientists have carefully characterized the mechanisms...
Apr, 01, 2006