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Mining Biomedical Literature: Using Computers to Extract Knowledge Nuggets

Researchers are not simply retrieving and repackaging what is already known, but are also deriving new knowledge by discovering connections that were previously unnoticed.

Not long ago, reading biomedical literature involved hours in the library combing through rows of dusty periodicals—not to mention pocketfuls of change for the copy machine. Now, although the...
Jul, 01, 2008
Genetic Variants and Ill Health: Scanning 500,000 SNPs Yields Gene-Disease Connections

It's an exhilarating time for genome-wide association studies

For the past few months it seemed you couldn’t open a journal without reading results of a new genome-wide association study. The results kept pouring in: four studies in April showing seven...
Oct, 01, 2007
Efficiently Evaluating Mathematical Expressions with OpenCL Code

A unique opportunity to build both flexibility and high performance into a piece of software.

OpenCL is a cross-platform language for doing general purpose computation on graphics processing units (GPUs) and other massively parallel architectures. One of its most interesting features is the...
Apr, 01, 2010
Simbios: Bringing Biomedical Simulation to Your Fingertips

How Simbios' state-of-the-art software tools are contributing to high-impact biomedical research

Simbios began with a simple idea: that physics-based simulation of biological structures at all scales could benefit from a unified tool-building effort.   At the same time, the thinking went,...
Oct, 01, 2009
OpenMM User Profile: Jesus Izaguirre, PhD

Notre Dame’s Jesus Izaguirre collaborates with Simbios to increase the time scales of protein folding simulations with OpenMM. Why team up with Simbios? Because “they are working on exciting problems and have good people,” he says.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Jesus Izaguirre, PhD, associate professor of computer science and engineering at the...
Oct, 01, 2009
NCBCs Take Stock and Look Forward: Fruitful Centers Face Sunset

From hardened software to scientific productivity, the NCBCs have changed the landscape for biomedical computing.  What will happen when their funding expires?

It has been eight years since the National Institutes of Health (NIH) funded the first National Centers for Biomedical Computing (NCBCs). With two or three years remaining in the program (...
ccb, i2b2, Magnet, na-mic, ncbo, NCIBI, Simbios
Oct, 19, 2012
2012 Update on the National Centers for Biomedical Computing

The Principal Investigators weigh in

Ever since the National Institutes of Health (NIH) began funding the National Centers for Biomedical Computing (NCBCs) just over seven years ago, these powerhouses have been plugging away, building...
NCBC
Feb, 29, 2012
OpenSim User Profile: Silvia Blemker, PhD

Simbios broadened University of Virginia’s Silvia Blemker’s horizons; and OpenSim is helping her understand hamstring injuries in sprinters.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Silvia Blemker, PhD, has deep roots in Simbios. As a Stanford graduate student, she...
Oct, 01, 2009
Journey to the NIH: Insights and Inspirations from the 2012 NCBC Showcase

Postdocs get a glance at the entire field and their first inside view of NIH grant-making

If he were a graduate student now, Francis Collins would be studying computational biology. That’s what the Director of the National Institutes of Health (NIH) told a rapt audience at the...
Feb, 19, 2013
AlloPathFinder User Profile: Jung-Chi Liao

Columbia’s Jung-Chi Liao seeks pathways within proteins using AlloPathFinder, a Simbios tool he co-developed while at Stanford.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   As a Simbios post-doc, Jung-Chi Liao, PhD, sought to understand how a conformational...
Oct, 01, 2009
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