The first four National Centers for Biomedical Computing take off
WHY NATIONAL CENTERS?
Four National Centers for Biomedical Computing were launched by the NIH in 2004 with $20 million in funding for each center over five years. The reason: We need to make...
Jun, 01, 2005
Atomistic simulations have the potential to elucidate the molecular basis of biological processes such as protein misfolding in Alzheimer’s disease or the conformational changes that drive...
Jan, 01, 2010
Computing airflow dynamics
We can’t see them, but tiny particles—dust, pollen, microbes, and the like—swirl around us in complicated, turbulent pathways. New numerical simulations suggest that, at least in...
Jun, 01, 2010
How errors in data, software, and methodology can teach us how to do better
In 2006, a paper in Nature Medicine suggested a novel and potentially revolutionary method for predicting patient responses to cancer therapies using gene signatures. The finding piqued the interest...
Sep, 01, 2011
Notre Dame’s Jesus Izaguirre collaborates with Simbios to increase the time scales of protein folding simulations with OpenMM. Why team up with Simbios? Because “they are working on exciting problems and have good people,” he says.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Jesus Izaguirre, PhD, associate professor of computer science and engineering at the...
Oct, 01, 2009
Supercomputers open up new horizons, offering the possibility of discovering new ways to understand life’s complexity
Their very names sound like dinosaurs. Teracomputers. Petacomputers. These are, in fact, the dinosaurs of the digital world—monstrous, hungry and powerful. But unlike the extinct...
Oct, 01, 2006
Assuring accuracy and efficiency
In simulations of human activities such as running, hundreds of individual musculotendon models turn on and off to swing the arms and legs. Naturally, these simulations can only be as accurate and...
Jun, 19, 2013
2-D computer simulation reveals unexpected pathway
What goes into the stomach must come out, but perhaps not in the same order in which it entered, as gastroenterologists have long assumed. A two-dimensional computer model of human stomach digestion...
Jan, 01, 2007
The Principal Investigators weigh in
Ever since the National Institutes of Health (NIH) began funding the National Centers for Biomedical Computing (NCBCs) just over seven years ago, these powerhouses have been plugging away, building...
Feb, 29, 2012
The Millisecond is Attained!
Scientists have now simulated protein folding at a timescale that begins to be relevant to biology: the millisecond. Indeed, the simulation busted through the millisecond time barrier to tackle the...
Apr, 01, 2010