The National Institutes of Health Roadmap for Medical Research has recently completed the first stage of an ambitious program to expand the computational infrastructure and software tools needed to...
Jan, 01, 2006
For a century, neuroscientists have dissected, traced, eavesdropped on, and are now compiling a seemingly endless cast of players in the nervous system. As we keep gathering more and more molecular...
Apr, 01, 2009
Biomechanical models contribute to a better understanding of both the normal and the diseased eye.
Squint, and you can almost make out that bird soaring over the horizon. But determining whether it’s a hawk or a raven will be nearly impossible for someone with myopia, also known as...
Feb, 19, 2013
How errors in data, software, and methodology can teach us how to do better
In 2006, a paper in Nature Medicine suggested a novel and potentially revolutionary method for predicting patient responses to cancer therapies using gene signatures. The finding piqued the interest...
Sep, 01, 2011
A new application automates MSM visualization
An unfolded protein can move through thousands of intermediate structures (conformations) before finding its properly folded state. One approach to understanding this process involves simulating a...
Feb, 19, 2013
How to deal with too many dimensions and too few samples.
Noninvasive experimental techniques, such as magnetic resonance (MR), infrared, Raman and fluorescence spectroscopy, and more recently, mass spectroscopy (proteomics) and microarrays (genomics) have...
Sep, 01, 2005
Synthetic biologists explain cell behaviors while desinging new ones
Without synchronized clocks—whether embedded in our body’s cells or programmed into our desktop computers—any kind of coordinated activity is impossible. So after synthetic...
Apr, 01, 2010
Collaborations are a fact of life for interdisciplinary fields like biomedical computing, and social scientists can help researchers understand how to make them more productive
Social scientists who study science have noticed a trend: More and more researchers are collaborating. Over the last twenty years, the number of co-authored papers has increased in every scientific...
Jul, 01, 2008
Through RNABuilder, Simbios brings computational modeling to Rick Russell’s lab at the University of Texas.
from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips
Rick Russell, PhD, associate professor of chemistry and biochemistry at the...
Oct, 01, 2009
Describing information flow within cells
Like corporate and governmental organizations, cells rely on middle managers to keep things running smoothly. These “middle managers” function as a critical bridge that controls the flow...
Jun, 01, 2010