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Where Tuberculosis Meets Computation: 10 Points of Intersection

Computation offers a window into a disease often described as a black box

The growing threats of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) are spurring worldwide interest in faster and more innovative research approaches, such as...
Jun, 06, 2012
Putting Heads Together

Upcoming biocomputing conferences

The 6th Annual International Conference on Computational Systems Bioinformatics (CSB2007) coordinated by the Life Sciences Society. WHAT: This conference is designed for any scientist interested in...
Jul, 01, 2007
Follow the Money: Big Grants in Biomedical Computing

A virtual lab rat; simulated DNA; an artificial pancreas; & integrating mental health data

Several biomedical computing projects received multi-million dollar funding in the fall of 2011, including efforts to: simulate the cardiac physiology of the rat; build a state-of-the-art DNA...
diabetes, DNA, Orozco, pancreas
Jan, 02, 2012
The Top Ten Advances of the Last Decade & The Top Ten Challenges of the Next Decade

A recognition of biocomputing's successes and a prediction of what's to come

The last ten years have seen huge leaps in biomedical computing. We now have new ways to integrate and understand vast quantities of data; the capacity for multi-scale biological modeling; and a...
bioinformatics tools, biomedical computing, CAD, computational modeling, data mining, disease surveillance, dynamic modeling, education, eric jakobsson, function prediction, genetic association, genome annotation, in silico screening, medical informatics, neuromodeling, prosthetics, sequence alignment, structure prediction, systems biology, systems biomedicine, telemedicine, tomography
Jun, 01, 2005
Getting It Right: Better Validation Key to Progress in Biomedical Computing

Bringing models closer to reality

When the ill-fated space shuttle Columbia launched on January 16, 2003, a large piece of foam fell off and hit the left wing. Alerted of the impact, NASA engineers used a computer model to predict...
7009, competitions, outsource, self-assessment, validation
Oct, 19, 2012
Clinical Decision Support: Providing Quality Healthcare with Help from a Computer
In a classic cartoon, a physician offers a second opinion from his computer.  The patient looks horrified: How absurd to think that a computer could have better judgment than a human doctor! But...
Jan, 01, 2010
Mining Biomedical Literature: Using Computers to Extract Knowledge Nuggets

Researchers are not simply retrieving and repackaging what is already known, but are also deriving new knowledge by discovering connections that were previously unnoticed.

Not long ago, reading biomedical literature involved hours in the library combing through rows of dusty periodicals—not to mention pocketfuls of change for the copy machine. Now, although the...
Jul, 01, 2008
BIOSURVEILLANCE: From Text-mining to Freakidemiology

Researchers are expanding the types of data that can be used to predict infectious disease spread; developing novel ways to analyze that data; and trying to create systems that can help address public health problems today

American officials are seeking better ways to anticipate public health crises following ten years that have seen outbreaks of SARS, avian flu, H1N1, West Nile virus, cholera and, most recently,...
biosurveillance
Apr, 01, 2011
Scale-Free Networks in Contemporary Biology
A standard dictionary definition of a network is “an interconnected or interrelated chain, group, or system.” A cursory look at our surroundings shows that networks are ubiquitous. For...
Oct, 01, 2007
Matters of Time: Tick Tock Go the Simulations

Computing using time steps -- a necessary approximation

Time flows like a continuous, steady river. And it moves forward—never back. These facts create inherent challenges for computer simulations of biological molecules in motion.   It would...
molecular dynamics, timesteps
Jun, 19, 2013
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