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BIOSURVEILLANCE: From Text-mining to Freakidemiology

Researchers are expanding the types of data that can be used to predict infectious disease spread; developing novel ways to analyze that data; and trying to create systems that can help address public health problems today

American officials are seeking better ways to anticipate public health crises following ten years that have seen outbreaks of SARS, avian flu, H1N1, West Nile virus, cholera and, most recently,...
biosurveillance
Apr, 01, 2011
2012 Update on the National Centers for Biomedical Computing

The Principal Investigators weigh in

Ever since the National Institutes of Health (NIH) began funding the National Centers for Biomedical Computing (NCBCs) just over seven years ago, these powerhouses have been plugging away, building...
NCBC
Feb, 29, 2012
Microarrays: The Search For Meaning in a Vast Sea of Data

They've gone from hype to backlash. Now it's time for reality: How microarrays are being used to benefit healthcare

When DNA microarray technology emerged more than a decade ago, it was met with unbridled enthusiasm. By allowing scientists to look at the expression of enormous numbers of genes in the genome...
Oct, 01, 2006
The Last Word
Dear Reader:   Welcome to the first issue of Biomedical Computation Review. With this quarterly publication, we hope to inspire and bring together scientists from the many fields that touch on...
Jun, 01, 2005
NIH Announcement: Big Data Gets Big Support

The new Big Data to Knowledge (BD2K) program signals NIH's faith in computational research

In December, the National Institutes of Health (NIH) approved a new trans-NIH initiative called Big Data to Knowledge (BD2K). With this action, the NIH signals its intention to invest a significant...
Feb, 19, 2013
Neurons Seek Their Own Solution

Computer models find that various ion channel arrangements can produce the same firing pattern

Each cell in our nervous system is an instrument in a complex symphony of electrophysiologic communication. A neuron’s signaling abilities arise from its array of ion channels—tunnels...
Jan, 01, 2007
Multiscale Modeling in Biomedical Research

New approaches extend multiscale models to represent cellular mesoscales and bridge from molecular to cellular models

In an era of increasingly comprehensive molecular characterizations of living systems, computation has emerged as a key technology to facilitate integrative understanding of biological mechanisms....
Feb, 19, 2013
The Microbiome: Dealing with the Data Deluge

Bioinformatics and computational biology enable microbiome research

This past June, 200 members of the NIH-funded Human Microbiome Project (HMP) Consortium published a slew of papers offering fresh insights into the role microbial communities play in the human body...
JGI, microbiome
Oct, 22, 2012
Reliable Models Now Available

Biomodels curates and annotates models for public use

As systems biologists develop models that attempt to simulate life, they need a good way to make them accessible to others as well as a good way to access other people’s models—and to...
Sep, 01, 2005
Art That's A BLAST

Ecce Homology is a physically interactive new-media work that visualizes genetic data as calligraphic forms.

A group of artists and scientists has created an interactive artwork using BLAST (Basic Local Alignment Search Tool), one of the foundational algorithms for comparative genomics. Normally, the BLAST...
Sep, 01, 2005
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