Dear Reader:
Welcome to the first issue of Biomedical Computation Review. With this quarterly publication, we hope to inspire and bring together scientists from the many fields that touch on...
Jun, 01, 2005
How to deal with too many dimensions and too few samples.
Noninvasive experimental techniques, such as magnetic resonance (MR), infrared, Raman and fluorescence spectroscopy, and more recently, mass spectroscopy (proteomics) and microarrays (genomics) have...
Sep, 01, 2005
Ecce Homology is a physically interactive new-media work that visualizes genetic data as calligraphic forms.
A group of artists and scientists has created an interactive artwork using BLAST (Basic Local Alignment Search Tool), one of the foundational algorithms for comparative genomics. Normally, the BLAST...
Sep, 01, 2005
Imaging, geometric modeling, representation and computing of shapes and forms are important components of modern computational biology. These processes apply across wide spectra of scales,...
Oct, 03, 2012
A novel approach to publishing for large research projects
When a large research project generates lots of data over a long time, that data can tell many different stories. Such was the case when the ENCODE (Encyclopedia of DNA Elements) project geared up to...
Oct, 22, 2012
Explaining biocomputation to non-scientists can leave a person tongue-tied. Technical jargon gets in the way, and the breadth of the field resists encapsulation.
To help out, and to reach out...
Oct, 01, 2007
Helping newcomers understand the lay of the land
As a program manager in biomedical computing and computational biology at the National Institutes of Health, I field many questions, particularly from new investigators. They ask questions like:...
Apr, 01, 2010
Anyone who has ever waited minutes, hours, or even days for software to complete a biomedical computation will be happy to hear that almost every personal computer is capable of better. Today,...
Jul, 01, 2008
Central repository of information on genes and proteins requires participation by the scientific community
If you build it, will they come? That’s the question on everyone’s mind after the launch of two pioneering initiatives in community annotation: WikiProteins and Gene Wiki, announced,...
Oct, 01, 2008
A safe haven for asking fundamental, wide-ranging questions
In the summer, it can be hard to find a place to sit at the Santa Fe Institute. Much of the year, only about a dozen researchers make their home at the multidisciplinary research organization. But in...
Oct, 01, 2006