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Zooming In on Blood Coagulation and Viscosity: Computation Takes On Blood Behavior

Simulations illuminate the inner workings of blood at multiple levels

Understanding blood flow and coagulation is crucial to treating blood disorders such as hemophilia and thrombosis, and to dealing with diseases such as AIDS, malaria, and diabetes that have...
Jun, 07, 2012
Understanding Molecular Kinetics with Markov State Models
Atomistic simulations have the potential to elucidate the molecular basis of biological processes such as protein misfolding in Alzheimer’s disease or the conformational changes that drive...
Jan, 01, 2010
Profiles in Computer Science Courage Part I: Reflections on the rewards of plunging into biomedicine

Interviews with Leonidas Guibas, Ron Shamir, Michael Black, David Haussler, Daphne Koller, Erin Halperin, Gene Myers, Paul Groth and Bruce Donald

To a computer scientist, the fields of biology and medicine can seem like the vast Pacific Ocean, says Leonidas Guibas, PhD, professor of computer science at Stanford University. “You go to the...
Careers, computer science
Apr, 01, 2011
Taking the leap: from single genes to the molecular choreography of the cell
The Human Genome Project has spurred extraordinary developments in our ability to characterize cellular systems in high-throughput fashion. Polymorphism, methylation, gene expression, and proteomics...
Apr, 01, 2008
Flexible Molecular Computer Functions Inside a Cell
A newly created molecular computer works in human cells and offers the flexibility of a general-purpose circuit. The advance, described in Nature Biotechnology in May, brings closer the eventual...
Oct, 01, 2007
Animating Molecular Biology

Watching changes over time

These days, molecular biologists often gather data over a period of time—observing shifts as they occur inside groups of cells undergoing natural changes. The researchers then face the daunting...
Jun, 01, 2010
The Top Ten Advances of the Last Decade & The Top Ten Challenges of the Next Decade

A recognition of biocomputing's successes and a prediction of what's to come

The last ten years have seen huge leaps in biomedical computing. We now have new ways to integrate and understand vast quantities of data; the capacity for multi-scale biological modeling; and a...
bioinformatics tools, biomedical computing, CAD, computational modeling, data mining, disease surveillance, dynamic modeling, education, eric jakobsson, function prediction, genetic association, genome annotation, in silico screening, medical informatics, neuromodeling, prosthetics, sequence alignment, structure prediction, systems biology, systems biomedicine, telemedicine, tomography
Jun, 01, 2005
Simbios: Bringing Biomedical Simulation to Your Fingertips

How Simbios' state-of-the-art software tools are contributing to high-impact biomedical research

Simbios began with a simple idea: that physics-based simulation of biological structures at all scales could benefit from a unified tool-building effort.   At the same time, the thinking went,...
Oct, 01, 2009
Packing It All In: Curricula for Biomedical Computing

Balancing Breadth and Depth

The last decade saw a proliferation of training programs at the intersection of life science and computation, with more than 60 new degree and certificate programs launched in the United States alone...
Sep, 01, 2005
Misconceptions of Time

Getting the molecular dynamics car out of the garage

For those who are not practitioners of dynamical simulation methods, such as molecular dynamics (MD), one of the biggest misconceptions relates to time. Specifically, the mismatch between the...
molecular dynamics simulations, time
Jun, 19, 2013
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