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Big Data Analytics In Biomedical Research

Can the complexities of biology be boiled down to Amazon.com-style recommendations?  The examples here suggest possible pathways to an intelligent healthcare system with big data at its core.

“We have recommendations for you,” announces the website Amazon.com each time a customer signs in.   This mega-retailer analyzes billions of customers’ purchases—nearly $...
Jan, 02, 2012
SimVascular User Profile: Charles Taylor, PhD

Charles A. Taylor, PhD, associate professor of bioengineering at Stanford University, is PI for the cardiovascular dynamics project within Simbios.

from http://biomedicalcomputationreview.org/content/simbios-bringing-biomedical-simulation-your-fingertips   Cardiovascular disease is a primary source of morbidity and mortality in the United...
Oct, 01, 2009
Bringing the Fruits of Computation to Bear on Human Health: It’s a Tough Job but the NIH Has to Do It
The National Institutes of Health are on a mission: To understand and tackle the problems of human health. To make that daunting problem approachable, 15 of the 20 institutes divvy up human health...
Oct, 05, 2012
An Uphill Challenge
RunBot, already the world’s fastest bipedal robot, has now also learned to keep its balance when walking up ramps. “We have achieved a synthesis of different functionalities, between...
Oct, 01, 2007
Life in Motion: Simulation from Particles to People

Computational simulations of life in motion at every scale—molecular, cellular, tissue-level, and whole organism—are boosting our understanding of the role mechanics plays in controlling life.

From atoms and molecules to insects, dinosaurs, and humans, computational researchers are finding that much of life can be understood in mechanical terms. Indeed, the machines of life are...
Jan, 01, 2008
The Top Ten Advances of the Last Decade & The Top Ten Challenges of the Next Decade

A recognition of biocomputing's successes and a prediction of what's to come

The last ten years have seen huge leaps in biomedical computing. We now have new ways to integrate and understand vast quantities of data; the capacity for multi-scale biological modeling; and a...
bioinformatics tools, biomedical computing, CAD, computational modeling, data mining, disease surveillance, dynamic modeling, education, eric jakobsson, function prediction, genetic association, genome annotation, in silico screening, medical informatics, neuromodeling, prosthetics, sequence alignment, structure prediction, systems biology, systems biomedicine, telemedicine, tomography
Jun, 01, 2005
Zooming In on Blood Coagulation and Viscosity: Computation Takes On Blood Behavior

Simulations illuminate the inner workings of blood at multiple levels

Understanding blood flow and coagulation is crucial to treating blood disorders such as hemophilia and thrombosis, and to dealing with diseases such as AIDS, malaria, and diabetes that have...
Jun, 07, 2012
Visualization in Space and Time: Seamless Pipelines Now Available

Advances in visualization changing work flows for understanding molecular dynamics, tracking cell movements, and designing interventional procedures

The pathway from raw data to valuable visualization of molecules, cells or organs being simulated over time involves several potentially painstaking steps. Typically, researchers must generate a set...
atrial fibrillation, developmental biology, ePMV, patient-specific, visualization
Sep, 02, 2011
Journey to the NIH: Insights and Inspirations from the 2012 NCBC Showcase

Postdocs get a glance at the entire field and their first inside view of NIH grant-making

If he were a graduate student now, Francis Collins would be studying computational biology. That’s what the Director of the National Institutes of Health (NIH) told a rapt audience at the...
Feb, 19, 2013
Dealing With a Flood of Conformations Using MSMBuilder
In the world of molecular dynamics (MD), researchers often need to analyze and extract meaningful results from millions of conformations. Existing software for accomplishing this task focuses on...
Oct, 01, 2009
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Big Data Analytics In Biomedical Research

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AlloPathFinder User Profile: Jung-Chi Liao

Columbia’s Jung-Chi Liao seeks pathways within proteins using AlloPathFinder, a Simbios tool he co-developed while at Stanford.

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More Than Fate: Computation Addresses Hot Topics in Stem Cell Research

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DATA MINING  visualization

genomics  SIMULATION neuroscience

biomechanics Systems Biology

DRUG DISCOVERY Cancer DNA

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