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The Golden Age of Public Databases: Speeding Biomedical Discovery

Public databases impact not only how research is done but what kind of research is done in the first place.

The setting: a scientific conference in January 2008. The speaker, Bruce Ponder, MD, PhD, an oncology professor at Cambridge University, is describing a previously unknown link between a particular...
Oct, 01, 2008
Janelia Farm: Cultivating Scientists

Janelia farmers pursue novel, cross-disciplinary collaborations to work on long-term, unwieldy scientific problems difficult to tackle in a single laboratory

The folks at Howard Hughes Medical Institute who dreamed up Janelia Farm say it is as much a social innovation as a scientific one. “We are creating a different culture here,” says Gerald...
Jul, 01, 2006
Bacteria with Byte

AgentCell is the first simulation program to model a biochemical network at the molecular, single cell, and population levels simultaneously.

When a bacterium swims toward food, it follows a chaotic path, alternating between spinning randomly and driving forward, or ‘tumbling’ and ‘running.’ Computer scientists at...
Sep, 01, 2005
Welcome Back

About this issue of Biomedical Computation Review

One of the main goals of this magazine is to create and foster a sense of community among the diverse disciplines that make up biomedical computation (hence our tagline: diverse disciplines, one...
Sep, 01, 2005
Biocomputation Startups: Where Does Value Lie?

An opportunity and a challenge

When discussing biocomputation startups, there’s one thing people agree on: These days, they don’t generate much excitement among venture capitalists.   “In the 1990s, there...
Apr, 01, 2007
Teaching Resource: Computing Life
Explaining biocomputation to non-scientists can leave a person tongue-tied. Technical jargon gets in the way, and the breadth of the field resists encapsulation.   To help out, and to reach out...
Oct, 01, 2007
Computational Biology Catches the Flu: Modeling the bug, the host, the world
The flu virus is an evolutionary marvel. Teams of experts design an appropriate flu vaccine annually just to keep up with the microbe’s ability to evade the human immune system. Multiple...
Jul, 01, 2006
Lung Tumors Recap Developmental Patterns

Principal component analysis of gene expression signatures may help determine prognosis

Researchers have long speculated that many of the genetic programs responsible for rapid growth of tumors are also important for the growth that occurs during normal embryonic development.   Now...
Oct, 01, 2010
Automating Scientific Discovery

A robot that develops hypotheses of its own

Robots already have a place in many labs, automating tedious tasks such as pipetting samples. But a new system designed at Aberystwyth University in the United Kingdom has taken laboratory automation...
Jul, 01, 2009
Binary Breathing

2004 grant to create a 3-D model of the respiratory tract

In September 2004, researchers at Pacific Northwest National Laboratory (PNNL) in Richland, Washington, received a $10 million grant to create a three-dimensional imaging and computer model of how...
Jun, 01, 2005
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