Collaborations are a fact of life for interdisciplinary fields like biomedical computing, and social scientists can help researchers understand how to make them more productive
Social scientists who study science have noticed a trend: More and more researchers are collaborating. Over the last twenty years, the number of co-authored papers has increased in every scientific...
Jul, 01, 2008
The first four National Centers for Biomedical Computing take off
WHY NATIONAL CENTERS?
Four National Centers for Biomedical Computing were launched by the NIH in 2004 with $20 million in funding for each center over five years. The reason: We need to make...
Jun, 01, 2005
How increased coverage of the structure space is transforming the field of biology
When the human genome was completely sequenced in 2003, researchers were already pondering how biomedicine could make use of it. One hope was that the sequences would lead to a greater...
Jan, 01, 2010
Decades of steady progress in pharmacogenetics have unearthed hundreds of associations between genes and drug response. But the field has to solve some theoretical and practical issues before it can deliver on the promise of personalized drug therapy.
As algorithms go, it’s deceptively simple. Just add together eight weighted pieces of patient information—age, height, weight, race, data about two genes, and a pair of clinical...
Jul, 01, 2009
Connectivity Map helps connect drugs and diseases
Normal cells, diseased cells and cells on drugs share a common language: They all produce their own patterns of gene expression. And the patterns can be compared in useful ways—given a disease...
Jan, 01, 2007
Medicinal patches applied to the skin are an attractive route for drug delivery since they can release medicine slowly into the bloodstream and avoid being metabolized by the digestive system. Yet...
Oct, 01, 2009
Researcher coaxes long strands of DNA into predetermined geometric shapes
Designing nanostructures of DNA just got easier. Paul Rothemund, PhD, a senior research fellow at Caltech has found a way to coax a long strand of DNA into a predetermined geometric shape by mixing...
Jul, 01, 2006
Computation offers a window into a disease often described as a black box
The growing threats of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis (TB) are spurring worldwide interest in faster and more innovative research approaches, such as...
Jun, 06, 2012
2-D computer simulation reveals unexpected pathway
What goes into the stomach must come out, but perhaps not in the same order in which it entered, as gastroenterologists have long assumed. A two-dimensional computer model of human stomach digestion...
Jan, 01, 2007
Researchers at the Mayo Clinic and IBM have each built computer pipelines for extracting useful information from unstructured notes in patient charts, such as physician’s notes and pathology...
Jul, 01, 2009